Research Assistant II - Neurogenetics Research

Kennedy Krieger Institute, Inc.; Baltimore, Northern (MD, KY); Hybrid; USD 40,000 - 66,000; Full time

Job summary

Kennedy Krieger Institute in Baltimore seeks a Research Assistant II to support neural network dysfunction studies. The role involves reading literature, performing experiments, data analysis, and presenting findings.

You will plan experiments, draft manuscripts, and contribute to team presentations. Responsibilities include tissue culture with iPSC-derived neural cells, advanced imaging and electrophysiology, and maintaining rodent colonies under approved protocols.

Qualifications

• Bachelor’s degree in a science field is required.
• Two years’ tissue culture or molecular biology experience preferred.
• Experience in MATLAB, R and Phyton is preferred.

Responsibilities

• Perform tissue culture experiments using iPSC-derived neural cells.
• Use methods like fluorescent in situ hybridization, immunohistochemistry, Ca2+ imaging, and MEA recording.
• Conduct rodent experiments with surgical techniques, post-operative care, and behavioral studies per IACUC protocols.
• Manage a colony of transgenic mice, genotype samples, record genotypes, and manage breeders.
• Use microscopy and image analysis systems to collect data and analyze with R/GraphPad Prism.
• Plan experiments in coordination with the PI and other methods.
• Collaborate with lab members to advance the research.

Skills

MATLAB

R

Phyton

Education

Bachelor’s degree (science)

Job description

Overview

The Research Assistant II assists the PI with scientific studies to elucidate the cellular mechanisms of neural network dysfunction in genetic models of neurodevelopmental disorders. The Research Assistant is able to read and understand scientific literature, carry out experiments, work collaboratively, plan experiments, analyze data, draft the manuscript and make presentations to others about the work.

Responsibilities

1. Perform tissue culture experiments using iPSC derived neural cells.
2. Use methods such as fluorescent in situ hybridization, immunohistochemistry, Ca2+ imaging, and MEA recording.
3. Conduct experiments in rodents, using surgical techniques, post-operative care, behavioral studies and euthanasia, in accordance with IACUC-approved protocols and the Guide for the Care and Use of Experimental Animals.
4. Manage the colony of transgenic mice, obtaining samples for genotyping, maintaining accurate records of genotypes and breeding, and managing supply of breeders and mice required for experiments.
5. Use computerized microscopy and image analysis systems to collect experimental data; analyze data with statistics packages such as R and GraphPad Prism.
6. Design and plan experiments, in coordination with the PI, using above/other methods.
7. Work cooperatively with others in the laboratory to carry out collaborative research.

QUALIFICATIONS:

• Experience in MATLAB, R and Phyton is preferred.
• Training in animal surgical techniques, EEG placement and post-operative care is preferred

EDUCATION:

• Bachelor’s degree required, preferably in a science related field such as biology, neuroscience, psychology, biomedical engineering, computer science, or physics.

EXPERIENCE:

• Previous laboratory training and experience in any field of science is required.
• Two years’ experience with tissue culture, molecular biology, is preferred.

Minimum pay range

USD $40,043.12/Yr.

Maximum pay range

USD $66,204.53/Yr.

Vacancy ID 13486

Pos. Category Research & Laboratories

Job Location : Street 707 N Broadway

# of Hours 40.00

Job Locations US-MD-Baltimore

Pos. Type Regular Full Time

Department : Name Neurogenetics Research

Equal Opportunity Provider & Employer M/F/Disability/ProtectedVet