Research Scientist: HER2 RTK Cancer Biology

Jazz Pharmaceuticals; Durham (NC); On-site; USD 120,000 - 190,000; Full time

Job summary

Jazz Pharmaceuticals seeks a laboratory-based scientist to design and execute experiments on anticancer compounds with a focus on RTKs, preferably HER2. Responsible for documenting protocols, data, analyses, and conclusions per lab procedures.

This full-time role involves communicating research through publications, conference presentations, abstracts, and patent applications. The candidate will manage cell culture, perform in vitro efficacy and mechanism studies, develop reporter systems, and

Qualifications

• Expertise in receptor tyrosine kinase biology, preferably including HER2.
• Experience with oncology and pharmacology assays.
• Demonstrated ability to publish and present at conferences.

Responsibilities

• Design and execute experiments on RTK/HER2–driven anticancer models.
• Maintain cancer and normal cell line cultures and documentation.
• Create stable cell lines with CRISPR for signaling modulation.
• Develop reporter systems for molecular targets.
• Present results for internal and external communications.
• Assist in preparing conference abstracts and manuscripts.

Skills

RTK biology

HER2 signaling

Oncology experience

Pharmacology assays

Publications experience

Project management

CRISPR editing

Education

Ph.D. in cancer biology or related field

Tools

CRISPR-Cas9

Job description

Jazz Pharmaceuticals seeks a laboratory-based scientist to design and execute experiments on anticancer compounds with a focus on RTKs, preferably HER2. Responsible for documenting protocols, data, analyses, and conclusions per lab procedures.

This full-time role involves communicating research through publications, conference presentations, abstracts, and patent applications. The candidate will manage cell culture, perform in vitro efficacy and mechanism studies, develop reporter systems, and