Remote Senior Director, Oncology Pharmacology

Jazz Pharmaceuticals, Inc.; Philadelphia (Philadelphia County); Remote; USD 232,000 - 348,000; Full time

Benefits offered by this job

Medical, dental and vision insurance

401(k) retirement plan

Discretionary equity grants

Job summary

Jazz Pharmaceuticals is seeking an experienced Oncology Pharmacology Leader to drive nonclinical programs from discovery through regulatory submission. You will chair cross-functional teams across immuno-oncology modalities and coordinate CROs to ensure timely, compliant study execution.

The role requires deep preclinical oncology expertise, strong leadership, and ability to integrate data across nonclinical and clinical domains to inform dosing and translational strategies.

Qualifications

• Industry experience leading oncology pharmacology programs from discovery through IND/NDA submissions.
• Deep oncology preclinical background and familiarity with diverse modalities.
• Immuno-oncology expertise with relevant in vivo/in vitro models and endpoints.
• Experience coordinating CRO-led studies, protocol development, and regulatory support.

Responsibilities

• Lead scientific teams across oncology pharmacology from discovery to regulatory submissions.
• Design and execute efficacy, tolerability, mechanism of action, and biomarker studies.
• Collaborate with matrix teams including Clinical Development, Toxicology, and Regulatory Affairs.
• Mentor junior scientists and provide scientific leadership across programs.
• Coordinate CRO activities, timelines, and budgets for nonclinical studies.
• Prepare high-quality reports for IND/NDA/MAA submissions.

Skills

Oncology pharmacology

Leadership

I/O experience

Cross-functional collaboration

PK/PD understanding

Education

Ph.D. in biology/biochemistry/immunology/pharmacology

Tools

GraphPad Prism

Job description

Jazz Pharmaceuticals is seeking an experienced Oncology Pharmacology Leader to drive nonclinical programs from discovery through regulatory submission. You will chair cross-functional teams across immuno-oncology modalities and coordinate CROs to ensure timely, compliant study execution.

The role requires deep preclinical oncology expertise, strong leadership, and ability to integrate data across nonclinical and clinical domains to inform dosing and translational strategies.