Research Lab Tech - Lagier-Tourenne Lab

The General Hospital Corporation; Boston (MA); Presencial; USD 29.000 - 40.000; Jornada completa

Descripción de la vacante

The General Hospital Corporation in Boston is seeking a detail‑oriented laboratory assistant to support ALS and dementia research. You will perform DNA/RNA purification, PCR, gel electrophoresis, Western blots, CRISPR/Cas9 editing, and cell culture tasks under supervision, and help prepare manuscripts and reports.

Responsibilities include maintaining equipment, preparing samples, recording data, and ensuring safety and quality across experiments; prior lab experience is preferred, and successful

Formación

• Bachelor's Degree related field required.
• Experience in lieu of degree allowed.
• Prior lab experience 1–2 years preferred.
• Strong knowledge of laboratory techniques and procedures.
• Familiarity with common lab equipment and instruments.
• Proficient in data collection, analysis, and scientific software.
• Attention to detail, organization, and multitasking.
• Strong problem-solving and troubleshooting abilities.

Responsabilidades

• Perform laboratory experiments following established protocols.
• Prepare and handle samples, reagents, and solutions with safety in mind.
• Operate and maintain laboratory equipment and instruments.
• Record experimental data and maintain organized records.
• Compile and analyze data using appropriate methods.
• Assist in data interpretation and manuscript preparation.

Conocimientos

Attention to detail

Communication skills

Analytical skills

Laboratory techniques

Educación

Bachelor's Degree in related field

Experience in lieu of degree allowed

Herramientas

DNA purification

qPCR

Gel electrophoresis

Western blot

CRISPR/Cas9 editing

Cell culture (iPSC-derived neurons)

Descripción del empleo

Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The laboratory is seeking a motivated individual to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis and dementia. Under the minimal supervision of the Principal Investigator and other researchers of the team, the incumbent will contribute to multiple organizational aspects of the laboratory that include ordering common laboratory supplies, general maintenance of equipment, establishment of procedures to comply with health and safety regulations and development of protocols and SOPs. The incumbent will participate to the research activity of the lab and is expected to be fully engaged in the scientific projects, as well as participate to the scientific lab meetings. They will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, high throughput sequencing, CRISPR/Cas9 editing, lentiviral and mammalian cell cultures including iPSC-derived neurons. Experience in mouse handling and mouse histology is preferred but not necessary. They will be responsible for the analysis of the results and participate in the preparation of manuscripts.

The individual must pay attention to details, work independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team.

There is flexibility to hire at the Tech I or II level based on an individual's experience and skillset.

Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.

Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.

Essential Functions

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.

Qualifications

Education

Bachelor's Degree Related Field of Study required

Can this role accept experience in lieu of a degree? Yes

Experience

Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred

Knowledge, Skills and Abilities

• Strong theoretical and practical knowledge of laboratory techniques and procedures.
• Familiarity with common laboratory equipment and instruments used in research experiments.
• Proficiency in data collection, analysis, and scientific software tools.
• Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
• Strong problem-solving skills and the ability to troubleshoot technical issues.
• Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Remote Type: Onsite

Work Location: 114 16th Street

Scheduled Weekly Hours: 40

Employee Type: Regular

Work Shift: Day (United States of America)

Pay Range: $21.00 - $29.01/Hourly

Grade: 5