Research Lab Tech I

Massachusetts General Hospital; Somerville (MA); On-site; USD 24,000 - 30,000; Full time

Job summary

Mass General Brigham is seeking a motivated candidate to join the Stanton Laboratory in CGM at Massachusetts General Hospital (MGH). The role focuses on delivering genetic therapies to the brain using molecular biology techniques, with in vitro and in vivo assays as part of the project.

Prior research experience in biological assays and data analysis is valued. The position emphasizes hands-on lab work, record-keeping, and collaboration within a multi-disciplinary team in a dynamic research

Qualifications

• High School Diploma or Equivalent required; Bachelor's Degree in Biology preferred.
• Experience with ELISA, flow cytometry, and molecular biology techniques preferred.
• Experience with gene delivery, nanoparticle formulation, or in vitro/in vivo experiments is a plus.
• Strong data collection, analysis, and documentation skills.
• Excellent written and verbal communication.

Responsibilities

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.

Skills

Molecular biology techniques

In vitro/in vivo assays

Data analysis

Sample preparation

Attention to detail

Education

High School Diploma or Equivalent

Bachelor's Degree Biology

Job description

Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Stanton Laboratory in the Center for Genomic Medicine (CGM) at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group.

Our research group is utilizing molecular biology techniques to develop technologies that can enable drug and gene delivery to the brain. The BBB has prevented multiple drugs-and especially gene therapies- from reaching the brain. A significant number of neurological diseases and psychiatric disorders have genetic causes, which could be corrected using modern gene editing technologies. However, these therapies can only be effective once they are delivered to the impacted cells in the brain, which has continued to prove to be a challenge. The candidate who will join this project will join a team working on a delivery system that can deliver genetic therapies to the brain, which could allow the treatment of many currently untreatable diseases of the brain. We are heavily utilizing molecular biology techniques in our work, and your day to day work would entail significant amounts of molecular biology.

Qualifications

In this project you would perform work in:

• Molecular biology techniques.
• Gene delivery vehicle production and characterization.
• In vitro and in vivo assays for gene delivery.

Candidates from multiple backgrounds are invited to apply, including a B.S., M.S., or equivalent degree in:

• Biology
• Biological Engineering
• Biomedical Engineering
• Chemical Engineering
• Chemistry
• Materials Science/Engineering
• Molecular biology
• Neuroscience
• Psychology
• Pharmaceutical Sciences
• Related fields

Prior research experience is preferred in biological assays (ELISA, flow cytometry, etc.), molecular biology (e.g., reactions such as PCR reactions, sequencing, gel assays, etc.), nanoparticle formulation and screening, nucleic acid delivery, in vitro/in vivo experiments, and/or data analysis.

Does this position require Patient Care? No

Essential Functions

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research ndings and reports.

Education

• High School Diploma or Equivalent required and Bachelor's Degree Biology preferred
• Can this role accept experience in lieu of a degree? Yes

Experience

• Prior laboratory experience, either through academic coursework, internships, or employment. 1-2 years preferred

Knowledge, Skills and Abilities

• Strong theoretical and practical knowledge of laboratory techniques and procedures.
• Familiarity with common laboratory equipment and instruments used in research experiments.
• Prociency in data collection, analysis, and scientic software tools.
• Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
• Strong problem-solving skills and the ability to troubleshoot technical issues.
• Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges

Physical Requirements

• Standing Frequently (34-66%)
• Walking Frequently (34-66%)
• Sitting Occasionally (3-33%)
• Lifting Frequently (34-66%) 35lbs
• Carrying Frequently (34-66%) 20lbs - 35lbs
• Pushing Occasionally (3-33%)
• Pulling Occasionally (3-33%) Climbing Rarely (Less than 2%) Balancing
• Frequently (34-66%)
• Stooping Occasionally (3-33%)
• Kneeling Occasionally (3-33%)
• Crouching Occasionally (3-33%) Crawling Rarely (Less than 2%)
• Reaching Frequently (34-66%)
• Gross Manipulation (Handling) Frequently (34-66%)
• Fine Manipulation Fingering) Frequently (34-66%)
• Feeling Constantly (67-100%)
• Foot Use Rarely (Less than 2%)
• Vision - Far Constantly (67-100%)
• Vision - Near Constantly (67-100%)
• Talking Constantly (67-100%)
• Hearing Constantly (67-100%)

Remote Type

Onsite

Work Location

399 Revolution Drive

Scheduled Weekly Hours

0

Employee Type

Temporary

Work Shift

Day (United States of America)

Pay Range

$17.50 - $21.80/Hourly

Grade

2

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

EEO Statement

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.