Research Lab Tech - Lagier-Tourenne Lab

Mass General Brigham; Boston (MA); On-site; USD 29,000 - 40,000; Full time

Job summary

Mass General Brigham is seeking a motivated laboratory technician to join a team studying disease mechanisms for ALS and dementia. You will assist in ordering supplies, maintaining equipment, and developing SOPs while performing DNA/RNA purification, qPCR, gel electrophoresis, and other molecular biology techniques.

You will contribute to data analysis and manuscript preparation, working under supervision but with opportunities for independent project involvement.

Qualifications

• Bachelor's degree in a related field; degree equivalency may be considered.
• 1-2 years of laboratory experience preferred.
• Strong written and verbal communication skills and ability to work in a team.

Responsibilities

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.

Skills

Attention to detail

Data analysis

Communication skills

Lab techniques

Education

Bachelor's degree in a related field

Tools

qPCR

Gel electrophoresis

Western blot

CRISPR/Cas9

Lentiviral transduction

iPSC-derived neurons

Job description

Site

The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The laboratory is seeking a motivated individual to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis and dementia. Under the minimal supervision of the Principal Investigator and other researchers of the team, the incumbent will contribute to multiple organizational aspects of the laboratory that include ordering common laboratory supplies, general maintenance of equipment, establishment of procedures to comply with health and safety regulations and development of protocols and SOPs. The incumbent will participate to the research activity of the lab and is expected to be fully engaged in the scientific projects, as well as participate to the scientific lab meetings. They will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, high throughput sequencing, CRISPR/Cas9 editing, lentiviral and mammalian cell cultures including iPSC‑derived neurons. Experience in mouse handling and mouse histology is preferred but not necessary. They will be responsible for the analysis of the results and participate in the preparation of manuscripts. The individual must pay attention to details, work independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team. There is flexibility to hire at the Tech I or II level based on an individual's experience and skillset. Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data. Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.

Essential Functions

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.

Qualifications

Education: Bachelor's Degree Related Field of Study required. Can this role accept experience in lieu of a degree? Yes. Licenses and Credentials: Experience prior laboratory experience, either through academic coursework, internships, or employment, 1-2 years preferred.

Knowledge, Skills and Abilities

• Strong theoretical and practical knowledge of laboratory techniques and procedures.
• Familiarity with common laboratory equipment and instruments used in research experiments.
• Proficiency in data collection, analysis, and scientific software tools.
• Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
• Strong problem‑solving skills and the ability to troubleshoot technical issues.
• Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.

Additional Job Details (if applicable)

Remote Type: Onsite
Work Location: 114 16th Street
Scheduled Weekly Hours: 40
Employee Type: Regular Work Shift Day (United States of America)
Pay Range: $21.00 - $29.01/Hourly Grade 5

Benefits

In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth.

EEO Statement

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People‑Focused, half Performance‑Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Company Culture

Combat disease. Hold a hand. Help people. Impact the world. Mass General Brigham is a passionate, welcoming community where minds meet caring hearts. Come be a part of the world’s most powerful force in medicine, where every role is important in changing lives. Are you ready? Our history includes New England hospitals founded over 200 years ago, some of the first and most prestigious hospitals in the world. Built on the legacy of two leading academic medical centers, we’re more than a system—we’re leaders in the practice of medicine. Mass General Brigham is committed to serving the community. We are dedicated to enhancing patient care, teaching and research, and taking a leadership role as an integrated health care system. We recognize that increasing value and continuously improving quality are essential to maintaining excellence.