Research Associate, Pharmacology

Socket.dev; San Diego (CA); On-site; USD 65,000 - 90,000; Full time

Benefits offered by this job

Annual bonus program

Incentive stock option plan

401k with flat employer contribution

Comprehensive medical insurance

Dental and vision insurance

HSA, FSA, and supplemental plans

Unlimited PTO

Generous holiday schedule

Relocation assistance

Job summary

Janux Therapeutics, Inc. in San Diego seeks a Research Associate to develop and execute ligand binding assays and related in vitro methods to support PK sample analysis. The role involves hands-on execution, data analysis, and detailed documentation to advance drug candidates.

You will work under the Pharmacology group, collaborating to analyze large data sets, perform ELISA and cell-based assays, and ensure SOP-compliant results for translational research programs.

Qualifications

• Bachelor’s degree with minimum 2 years of relevant experience or Master’s with minimum 1 year of relevant industry experience.
• Experience in ligand binding assay development, qualification/validation and sample analysis.
• Competence in data analysis tools (Excel, GraphPad).
• Hands-on expertise with ELISA and MSD is desirable.
• Experience with cell-based assays is a plus.
• Experience with immunogenicity/ADA sample analysis is a plus.
• Ability to perform routine testing and to follow SOPs accurately.
• Strong analytical and written/spoken communication skills.

Responsibilities

• Identify, develop and execute ligand binding assays and other in vitro assays to support in vivo and in vitro pharmacology studies.
• Proven track record of ligand binding assay development and involvement in routine preclinical/clinical sample analysis; execute from development to data reporting.
• Analyze and present experimental data using Prism, Excel, MS Office or similar software.
• Produce detailed documentation of experiments in lab notebooks and electronically.
• Schedule and prioritize workload effectively within a multi-task environment.

Skills

Ligand binding assays

Data analysis (Excel, Prism)

ELISA

MSD

Cell-based assays

Documentation

Education

Bachelor's degree + 2 yrs of experience

Master's degree + 1 yr experience

Tools

GraphPad

Excel

Job description

As a member of the pharmacology group, we seek a scientifically curious and motivated individual with an ability to work in a fast-paced environment. The potential Research Associate will develop and execute the ligand binding assay based bioanalytical method development to support pharmacokinetics (PK) sample analysis. In addition, the candidate will have opportunity to analyze high volume of data and to develop in vitro assays for compound characterization using ELISA, Octet, and cell-based assays. This position is hands-on and requires the effective experiment execution, communication, and documentation of results that enable the advancement of novel research molecules toward development candidates. Strong candidates will be hard working, efficient, collaborative, and passionate about drug discovery and development. Experience in ligand binding assay development and routine sample analysis is desired. This position will report directly to the Scientist of in vivo Pharmacology.

ESSENTIAL FUNCTIONS AND RESPONSIBILITIES

• Identify, develop and execute ligand binding assays and other in vitro assays to support both in vivoand in vitropharmacology studies.
• Proven track record of ligand binding assay development and participation of routine preclinical and/or clinical sample analysis. Execute assays from assay development, qualification (if required), sample analysis, data analysis, and report by following the instruction or established procedure.
• Analyze and present experimental data using Prism, Excel, MS Office or similar software.
• Produce detailed documentation of experiments within a lab notebook and electronically.
• Ability to schedule and prioritize workload effectively within a multi-task environment.

EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES

• A bachelor’s degree with a minimum of 2 years of relevant experience or a master’s degree with a minimum of 1 year of relevant industry experience.
• Experience in ligand binding assay development, qualification/validation and sample analysis.
• Competence in data analysis tools (Excel, GraphPad). Candidates with experience in data management, coding and programming in Excel or other data management software would be a plus.
• Hands-on expertise with ELISA and MSD is highly desirable.
• Experience with cell-based assays is a plus.
• Experience with immunogenicity/ADA sample analysis is a plus.
• Ability to perform routine testing and to follow SOPs in a highly accurate and reproducible manner.
• Strong analytical and critical thinking skills with the ability to work in a fast-paced and collaborative environment.
• Excellent written and oral communication skills.

Job Type:

Full-time

Benefits:

• Annual bonus program
• Incentive stock option plan
• 401k plan with flat non‑elective employer contribution
• Comprehensive medical insurance with 90‑100% employer‑paid premiums
• Dental and vision insurance
• HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)
• Unlimited PTO
• Generous holiday schedule; includes summer and winter company shutdown
• Relocation assistance

Schedule:

• Monday to Friday

Work authorization:

• United States (Required)

Additional Compensation:

• Annual targeted bonus %

Work Location:

• On site (San Diego, CA)

EQUAL OPPORTUNITY EMPLOYER:

Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.