Research Associate, Next Gen Sequencing

Colossal Biosciences; Dallas (TX); On-site; USD 60,000 - 80,000; Full time

Benefits offered by this job

Medical, dental, and vision coverage

Flexible spending accounts (FSA)

Company matched 401k retirement plan

Paid parental leave

Education reimbursement

Job summary

Colossal Biosciences is seeking a Research Associate located in Dallas, TX, to support large-scale genome sequencing initiatives focused on species conservation and de-extinction. The role encompasses preparing samples, improving sequencing workflows, and utilizing robotic automation in high-throughput settings.

The ideal candidate will have a BA/BS with experience in biological research techniques and a proactive approach to problem-solving. The company offers competitive benefits, including medical coverage and generous paid time off.

Qualifications

• 1+ years of hands-on research in bioengineering, molecular biology, or genetics.
• Experience in library preparation for sequencing applications like WGS and mRNA-seq.
• Ability to work in a fast-paced environment while maintaining data accuracy.

Responsibilities

• Perform high-throughput sequencing workflows for genome conservation.
• Utilize robotic automation to enhance NGS workflows.
• Maintain a clean and organized laboratory space.

Skills

High-throughput nucleic acid purification

Liquid handling

Technical troubleshooting

Creativity and problem-solving

Data communication to stakeholders

Education

BA/BS in bioengineering, molecular biology, genetics, or related fields

Tools

Illumina MiSeq

NextSeq2000

Agilent Tape Station

Firefly Plus

Job description

The Research Associate will take on large-scale genome sequencing initiatives for species conservation and de-extinction. They will expand on tools and methodologies to optimize sequencing data flow while maintaining and enhancing workflows to track samples from submission to data delivery.

This position is based on-site in Dallas, TX. Relocation assistance is available.

Duties and Responsibilities

• Prepare samples and perform high-throughput targeted amplicon sequencing workflows
• Improve the state of the art of NGS for genome editing and genotyping
• Utilize and adapt robotic automation for NGS workflows (Firefly Plus)
• Maintain a working inventory for the sequencing core
• Maintain a thorough and detailed electronic lab notebook
• Maintain a clean and organized laboratory space

Required Skills and Abilities

• Capable of working in a fast-paced, high volume sequencing core on parallel projects, while maintaining accuracy and timely data transfer
• Experience with high-throughput nucleic acid purification and liquid handling (Ex. Firefly)
• Experience running HTP gel electrophoresis units (Ex. Agilent Tape Station)
• Self-motivated, flexible, proactive, works well under pressure and deadlines, detail-oriented
• Enthusiastic to learn new skills and take on new responsibilities
• Creative problem-solver who can perform technical trouble-shooting
• Communicates clearly and proactively to ensure data delivery to stakeholders

Preferred Experience

• Experience operating sequencing platforms (Ex. Illumina MiSeq, NextSeq2000)
• Comfortable with Illumina's Basespace and data transfer
• Experience in library preparation for NGS (genotyping), WGS, mRNA-seq, single cell-seq, ATAC-seq, and rhAMP-seq applications.

Education and Experience

• BA/BS with 1+ years of hands-on research in bioengineering, molecular biology, genetics or related fields, such as computational biology

What Colossal Offers Full-Time Employees

• Medical, dental, and vision coverage
• Excellent paid time off and company holidays so you can rest and recharge
• Flexible spending accounts (FSA)
• Company matched 401k retirement plan
• Paid parental leave at 100% salary for up to 12 weeks
• Education reimbursement
• An opportunity to help us return the Earth to a healthier state

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law