Research Associate in Antibody Discovery

Abilita Therapeutics, Inc.; San Diego (CA); On-site; USD 75,000 - 110,000; Full time

Benefits offered by this job

Competitive salary

Comprehensive benefits package

Stock options

Supportive work environment

Job summary

A biotechnology start-up is looking for a skilled Research Associate in Antibody Discovery to support laboratory experiments for drug development targeting membrane proteins. This role requires a Bachelor’s or Master’s degree in Molecular Biology, along with significant laboratory experience in antibody discovery and molecular biology techniques. The ideal candidate should thrive in a collaborative environment and is crucial for driving innovative therapeutic solutions. Competitive salary and benefits package offered, along with stock options.

Qualifications

• Minimum of 5 years of molecular biology experience.
• Minimum of 2 years of antibody discovery experience.
• Proficiency with cloning and sequencing.
• Hands-on experience with antibody display technologies (e.g., phage display or yeast surface display), including library construction and/or selection/panning (REQUIRED).
• Proficiency with cloning, sequencing, and basic molecular biology techniques (e.g. PCR, restriction enzymes).
• Demonstrated ability to independently design, implement, and troubleshoot experimental work in a laboratory.

Responsibilities

• Support antibody discovery efforts through lab experiments.
• Assist workflows including humanization and affinity maturation.
• Produce reliable data and maintain accurate lab records.
• Produce high-quality, reliable data and maintain accurate laboratory records.
• Operate and maintain the relevant equipment.
• Maintain close collaborative interactions with colleagues within the research group and regularly communicate progress to the team or supervisors.

Skills

Antibody display technologies

Molecular biology techniques

Strong organizational skills

Yeast display

Cloning

Sequencing

PCR

Restriction enzymes

Lab techniques

Data management

Education

Bachelor’s or Master’s degree in Molecular Biology

Tools

PCR

Sequencing

Job description

Abilita Therapeutics is an innovation-driven biotechnology start-up company focused on enabling the discovery and development of drugs targeting undruggable membrane proteins, including G Protein-Coupled Receptors (GPCRs), transporters and ion channels. With our proprietary technology, Abilita aims to discover and develop transformative therapeutics to treat a wide range of diseases. For more detailed information, visit our website at www.abilitatx.com.

Position Overview:

We are seeking a skilled and motivated Research Associate in Antibody Discovery to assist with challenging discovery campaigns across multiple targets. The ideal candidate will have hands-on experience in yeast display and/or phage display and mammalian tissue culture. The candidate will help build a unique pipeline of antibody therapeutic candidates. The successful candidate will be a proactive and resilient individual who thrives in a team-focused, cutting-edge environment.

Key Responsibilities:

• Support antibody discovery efforts by executing laboratory experiments related to library generation and panning campaigns.
• Assist with workflows including antibody characterization, engineering, humanization, affinity maturation, and all other lead optimization activities.
• Perform basic tissue culture operations to maintain, transfect, and harvest mammalian cell biomass.
• Produce high-quality, reliable data and maintain accurate, detailed laboratory records.
• Operate and maintain the relevant equipment.
• Maintain close collaborative interactions with colleagues within the research group and regularly communicate progress to the team or supervisors.

Qualifications:

• Bachelor’s or Master’s degree in Molecular Biology or a related field (REQUIRED).
• Minimum of 5 years of molecular biology experience (REQUIRED).
• Minimum of 2 years of antibody discovery experience in the laboratory (REQUIRED).
• Hands-on experience with antibody display technologies (e.g., phage display or yeast surface display), including library construction and/or selection/panning (REQUIRED).
• Proficiency with cloning, sequencing, and using basic molecular biology techniques (e.g. PCR, restriction enzymes).
• Demonstrated capability to independently design, implement, and troubleshoot experimental work in a laboratory.
• Strong organizational skills and attention to detail with a commitment to maintaining accurate lab records.
• Experience with library construction is a plus.
• Experience with bioinformatics tools for sequence analysis is a plus.

What We Offer:

• A competitive salary and comprehensive benefits package.
• Stock options, giving you a significant stake in the success and growth of our company.
• The opportunity to be part of a cutting-edge company that is making a real difference in the field of small-molecule and antibody therapeutics for undruggable membrane proteins.
• A dynamic and supportive work environment that values innovation, creativity, and passion.