Research Associate

Brown University; Rhode Island; On-site; USD 85,000 - 110,000; Full time

Job summary

Brown University in Rhode Island seeks a Research Associate to independently manage LC-MS/MS proteomics and small molecule analyses from project design to closeout. The role includes sample prep, instrument operation, data interpretation, and training for undergraduates within the Proteomics Core Facility.

Required: Master’s degree with 2–5 years’ related experience; strong MS/LC-MS, data interpretation, and communication skills. Fixed-term position with potential extension based on funding.

Qualifications

• Master’s degree in biology, biochemistry, analytical chemistry, proteomics, metabolomics, or closely related field.
• 2–5 years related experience required with MS and LC/MS workflows.
• Experience with technical guidance and communicating results to collaborators desired.
• Knowledge of proteins, chemistry, and biochemistry required.
• Experience with small molecule/metabolite LC/MS analysis strongly desired.

Responsibilities

• Manage projects from intake to closeout in the Proteomics Core Facility.
• Perform LC-MS/MS acquisition, sample prep, QC, and data evaluation.
• Provide technical oversight and training to undergraduate researchers.
• Coordinate client consultations and project follow-ups.
• Maintain documentation in iLabs and ensure accurate records.

Skills

Mass spectrometry

LC-MS workflows

Data interpretation

Client communication

Troubleshooting

Education

Master’s degree

Biology/biochemistry

Tools

Spectromine

Spectronaut

Proteome Discoverer

Job description

Job Description:The Research Associate is a specialized scientific staff member within the Proteomics Core Facility who independently manages assigned research projects from design/project intake through project closeout while supporting mass spectrometry -based proteomics and small molecule/metabolite analyses for a diverse research community. The Research Associate independently performs and coordinates sample preparation, LC-MS/MS acquisition, quality control, evaluates data, manages project status and intake documentation in iLabs, conducts client consultations including project closeouts/follow-up meetings, and provides technical oversight and training to undergraduate researchers. This cross-disciplinary role is essential to maintaining and expanding the Core’s analytical services which requires advanced knowledge of protein biochemistry, analytical chemistry, chromatography, high resolution mass spectrometry, data interpretation, and research project management.This is a fixed term position with a current end date of one year from the date of hire, which may be extended based upon available funding.Job QualificationsEducation and Experience (Grade 9):Required: Master’s degree in biology, biochemistry, analytical chemistry, proteomics, metabolomics, or a closely related field plus 2-5 years’ related experience.Demonstrated hands-on experience with mass spectrometry and LC/MS workflows, including sample preparation, method execution and optimization, LC-MS data acquisition and analysis, instrument operation and troubleshooting, and interpretation of experimental results. Experience providing technical support or guidance to research projects and communicating analytical results to scientific collaborators is also required.Knowledge of laboratory approaches and techniques in the areas of Proteins, Chemistry, and Biochemistry required.And/or equivalent combination of education and experience.Experience with small molecule or metabolite LC/MS analysis is strongly desired. Candidate must understand the distinct sample preparation, chromatographic, and acquisition requirements of peptide/protein vs metabolite workflows.Strong computer skills with experience using software for the analysis of protein mass spectrometry data is strongly advantageous, specifically Spectromine, Spectronaut, Proteome Discoverer.Experience working with proteins (i.e. Western Blots, BCAs, Purification, performing proteomic sample prep (e.g. Protifi S-Trap, In-solution digestion, Barocycler assisted-digestion, on-bead digestion, PreOmics etc.) is desirable.Education and Experience (Grade 10):Required: Master’s degree in biology, biochemistry, analytical chemistry, proteomics, metabolomics, or a closely related field plus 5-7 years’ related experience.Demonstrated hands-on experience with mass spectrometry and LC/MS workflows, including sample preparation, method execution and optimization, LC-MS data acquisition and analysis, instrument operation and troubleshooting, and interpretation of experimental results. Experience providing technical support or guidance to research projects and communicating analytical results to scientific collaborators is also required.Knowledge of laboratory approaches and techniques in the areas of Proteins, Chemistry, and Biochemistry required.Experience working with proteins (i.e. Western Blots, BCAs, Purification, performing proteomic sample prep (e.g. Protifi S-Trap, In-solution digestion, Barocycler assisted-digestion, on-bead digestion, PreOmics etc.) required.And/or equivalent combination of education and experience.Experience with small molecule or metabolite LC/MS analysis is strongly desired. Candidate must understand the distinct sample preparation, chromatographic, and acquisition requirements of peptide/protein vs metabolite workflows.Strong computer skills with experience using software for the analysis of protein mass spectrometry data is strongly advantageous, specifically Spectromine, Spectronaut, Proteome Discoverer.Job Competencies:Availability to receive and process user samples during Core Facility Operation Hours (M-F, 9-5PM)Excellent written, verbal, and client-facing communication skills.• Ability to be observant and self-motivated.Ability to think critically and problem-solve including sample preparation and instrument troubleshooting.Ability to work independently.Ability to complete accurate records and follow detailed instructions.CRIMINAL BACKGROUND AND EDUCATION CHECK REQUIRED.Benefits of Working at Brown:Please review additional information on the Benefits of Working at Brown.Recruiting Start Date:2026-09-01Job Posting Title:Research AssociateDepartment:Department of Molecular Biology, Cell Biology and BiochemistryGrade:Grade 9Worker Type:EmployeeWorker Sub-Type:Fixed Term (Fixed Term)Time Type:Full timeScheduled Weekly Hours:37.5Position Work Location:OnsiteSubmission Guidelines:The designated Position Work Location for each position determines the approved modality of work. Positions are classified based on the operational and business needs of the department and may be designated as on-site, hybrid, or remote.Employees with a designated position work location as remote must reside and perform their work in a state where Brown University is registered to do business. Brown University is a registered employer in the following states: Rhode Island, California, Colorado, Connecticut, Florida, Maryland, Massachusetts, New York, New Hampshire, New Jersey, North Carolina, Washington, D.C.Please note that to be considered for a staff position at Brown University, you must submit a separate application for each position you wish to be considered for. Applications are reviewed only for the specific position to which they are submitted and are not automatically considered for future openings.This position is not eligible for visa sponsorship.Still Have Questions?If you have any questions you may contact [e-mail] is an E-Verify Employer.EEO Statement:Brown University provides equal opportunity and prohibits discrimination, harassment and retaliation based upon a person’s race, color, religion, sex, age, national or ethnic origin, disability, veteran status, sexual orientation, gender identity, gender expression, or any other characteristic protected under applicable law, in the administration of its policies, programs, and activities. The University recognizes and rewards individuals on the basis of qualifications and performance. The University maintains certain affirmative action programs in compliance with applicable law.