Research Associate

Brown University; Providence (RI); On-site; USD 85,000 - 115,000; Full time

Job summary

Brown University’s Proteomics Core Facility seeks a Research Associate who will independently manage assigned research projects from design through closeout while supporting mass spectrometry-based proteomics and small molecule analyses for a diverse research community.

The role requires advanced knowledge of protein biochemistry and analytical chemistry, and involves data evaluation, client consultations, and training of undergraduate researchers.

Qualifications

• Master's degree with 2–5 years' related MS-based proteomics experience.
• Hands-on MS and LC/MS workflows; data analysis and instrument troubleshooting.
• Experience guiding projects and communicating results to collaborators.
• Knowledge of proteins, chemistry, and biochemistry.
• Experience with small molecule/metabolite LC/MS analysis is strongly desired.
• Strong computer skills for protein mass spectrometry data analysis.

Responsibilities

• Manage sample preparation and LC-MS/MS acquisition.
• Conduct quality control and data interpretation of results.
• Maintain project status and intake documentation in iLabs.
• Provide client consultations and follow-up meetings.
• Train undergraduate researchers and provide technical oversight.

Skills

Mass spectrometry

LC-MS workflows

Protein biochemistry

Analytical chemistry

Chromatography

Data interpretation

Project management

Education

Master's degree in biology/biochemistry/analytical chemistry/proteomics/metabolomics

Tools

Spectronaut

Spectromine

ProteomeDiscoverer

iLabs

Job description

Research Associate

Brown University

Job Description

The Research Associate is a specialized scientific staff memberwithin the Proteomics Core Facility who independently managesassigned research projects from design/project intake throughproject closeout while supporting mass spectrometry -basedproteomics and small molecule/metabolite analyses for a diverseresearch community. The Research Associate independently performsand coordinates sample preparation, LC-MS/MS acquisition, qualitycontrol, evaluates data, manages project status and intakedocumentation in iLabs, conducts client consultations includingproject closeouts/follow-up meetings, and provides technicaloversight and training to undergraduate researchers. Thiscross-disciplinary role is essential to maintaining and expandingthe Core's analytical services which requires advanced knowledge ofprotein biochemistry, analytical chemistry, chromatography, highresolution mass spectrometry, data interpretation, and researchproject management.

This is a fixed term position with a current end date of one yearfrom the date of hire, which may be extended based upon availablefunding.

Job Qualifications

Education and Experience (Grade 9)

• Required: Master's degree in biology, biochemistry, analyticalchemistry, proteomics, metabolomics, or a closely related fieldplus 2-5 years' related experience.
• Demonstrated hands-on experience with mass spectrometry andLC/MS workflows, including sample preparation, method execution andoptimization, LC-MS data acquisition and analysis, instrumentoperation and troubleshooting, and interpretation of experimentalresults. Experience providing technical support or guidance toresearch projects and communicating analytical results toscientific collaborators is also required.
• Knowledge of laboratory approaches and techniques in the areasof Proteins, Chemistry, and Biochemistry required.
• And/or equivalent combination of education and experience.
• Experience with small molecule or metabolite LC/MS analysis isstrongly desired. Candidate must understand the distinct samplepreparation, chromatographic, and acquisition requirements ofpeptide/protein vs metabolite workflows.
• Strong computer skills with experience using software for theanalysis of protein mass spectrometry data is stronglyadvantageous, specifically Spectromine, Spectronaut, ProteomeDiscoverer.
• Experience working with proteins (i.e. Western Blots, BCAs,Purification, performing proteomic sample prep (e.g. ProtifiS-Trap, In-solution digestion, Barocycler assisted-digestion,on-bead digestion, PreOmics etc.) is desirable.

Education and Experience (Grade 10)

• Required: Master's degree in biology, biochemistry, analyticalchemistry, proteomics, metabolomics, or a closely related fieldplus 5-7 years' related experience.
• Demonstrated hands-on experience with mass spectrometry andLC/MS workflows, including sample preparation, method execution andoptimization, LC-MS data acquisition and analysis, instrumentoperation and troubleshooting, and interpretation of experimentalresults. Experience providing technical support or guidance toresearch projects and communicating analytical results toscientific collaborators is also required.
• Knowledge of laboratory approaches and techniques in the areasof Proteins, Chemistry, and Biochemistry required.
• Experience working with proteins (i.e. Western Blots, BCAs,Purification, performing proteomic sample prep (e.g. ProtifiS-Trap, In-solution digestion, Barocycler assisted-digestion,on-bead digestion, PreOmics etc.) required.
• And/or equivalent combination of education and experience.
• Experience with small molecule or metabolite LC/MS analysis isstrongly desired. Candidate must understand the distinct samplepreparation, chromatographic, and acquisition requirements ofpeptide/protein vs metabolite workflows.
• Strong computer skills with experience using software for theanalysis of protein mass spectrometry data is stronglyadvantageous, specifically Spectromine, Spectronaut, ProteomeDiscoverer.

Job Competencies

• Availability to receive and process user samples during CoreFacility Operation Hours (M-F, 9-5PM)
• Excellent written, verbal, and client-facing communicationskills.• Ability to be observant and self-motivated.
• Ability to think critically and problem-solve including samplepreparation and instrument troubleshooting.
• Ability to work independently.
• Ability to complete accurate records and follow detailedinstructions.

CRIMINAL BACKGROUND AND EDUCATION CHECK REQUIRED.

Benefits of Working at Brown

Please review additional information on the Benefits of Working at Brown.

Recruiting Start Date

2026-09-01

Job Posting Title

Research Associate

Department

Department of Molecular Biology, Cell Biology andBiochemistry

Grade

Grade 9

Worker Type

Employee

Worker Sub-Type

Fixed Term (Fixed Term)

Time Type

Full time

Scheduled Weekly Hours

37.5

Position Work Location

Onsite

Submission Guidelines

The designated Position Work Location for each position determines the approved modality of work. Positions are classified based on the operational and business needs of the department and may be designated as on-site, hybrid, or remote. Employees with a designated position work location as remote must reside and perform their work in a state where Brown University is registered to do business. Brown University is a registered employer in the following states: Rhode Island, California, Colorado, Connecticut, Florida, Maryland, Massachusetts, New York, New Hampshire, New Jersey, North Carolina, Washington, D.C.

This position is not eligible for visa sponsorship.

Still Have Questions?

If you have any questions you may contact [e-mail].

Brown is an E-Verify Employer

Brown is an E-Verify Employer.

EEO Statement

Brown University provides equal opportunity and prohibitsdiscrimination, harassment and retaliation based upon a person'srace, color, religion, sex, age, national or ethnic origin,disability, veteran status, sexual orientation, gender identity,gender expression, or any other characteristic protected underapplicable law, in the administration of its policies, programs,and activities. The University recognizes and rewards individualson the basis of qualifications and performance. The Universitymaintains certain affirmative action programs in compliance withapplicable law.