Remote R&D Scientist — Immunohistochemistry & Histology

Natera

San Carlos (CA)

Remote

USD 125,000 - 140,000

Full time

3 days ago
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Benefits offered by this job

Medical benefits
Fertility care benefits
401k plan
Employee genetic testing benefits

Job summary

Natera is seeking a Scientist, R&D – Immunohistochemistry (IHC) & Histology to advance IHC and tissue-based workflows for oncology products and clinical assay development. The role emphasizes hands-on IHC assay development, histology, and use of automated platforms like Roche BenchMark ULTRA, with exposure to NGS and molecular workflows as a plus.

The candidate will design studies, optimize assays, and collaborate across Pathology, CL Operations, QA, and Automation to translate methods into

Qualifications

  • Ph.D. in Pathology, Cancer Biology, Molecular Biology, Cell Biology, Biomedical Sciences, or a related field with minimum 2 years of industry experience; or Master's with 5+ years; or Bachelor's with 6-8+ years.

Responsibilities

  • Design and execute development, verification, and validation studies for IHC and histology workflows.
  • Develop and optimize IHC assays, including antibody selection, titration, antigen retrieval, staining conditions, and controls.
  • Evaluate histology variables (FFPE processing, embedding, sectioning, H&E) and slide preparation.
  • Troubleshoot workflows on automated IHC/ISH platforms and investigate artifacts and variability.
  • Plan moderate- to high-complexity experiments and analyze results using Excel, JMP, or image analysis tools.
  • Collaborate with cross-functional teams to transfer R&D methods to clinical lab workflows.
  • Author study protocols, validation reports, SOPs, and provide training during implementation.
  • Communicate progress, findings, risks, and recommendations to project teams.

Job description

Natera is seeking a Scientist, R&D – Immunohistochemistry (IHC) & Histology to advance IHC and tissue-based workflows for oncology products and clinical assay development. The role emphasizes hands-on IHC assay development, histology, and use of automated platforms like Roche BenchMark ULTRA, with exposure to NGS and molecular workflows as a plus.

The candidate will design studies, optimize assays, and collaborate across Pathology, CL Operations, QA, and Automation to translate methods into

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