Remote Global Director, Clinical Operations

Remote; San Francisco (CA); Remote; USD 180,000 - 240,000; Full time

Benefits offered by this job

Remote work

Travel opportunities

Job summary

Amylyx is seeking a Director of Clinical Operations to lead global trial execution with responsibility for planning, budgeting, quality and compliance. You will translate program strategy into executable operational plans and drive timelines and risk management across studies.

The role requires expert leadership in CRO/vendor oversight, cross-functional collaboration, and the ability to work in a fast-paced, small company environment. Domestic travel up to 20% is expected.

Qualifications

• BS/BA degree in science or health-related field preferred.
• Extensive clinical operations experience in pharma/biotech or CRO.
• Strong vendor management and regulatory knowledge (ICH-GCP, GDPR).

Responsibilities

• Provide end-to-end operational leadership for global clinical trials.
• Oversee study plans, timelines, resources, and risk mitigation.
• Manage CROs, vendors, and outsourcing strategies with finance and legal.

Skills

Project management

Vendor management

Risk-based decisions

Communication skills

Clinical operations leadership

Education

BS/BA degree in science or health-related field

Tools

Remote data capture tools

Job description

Amylyx is seeking a Director of Clinical Operations to lead global trial execution with responsibility for planning, budgeting, quality and compliance. You will translate program strategy into executable operational plans and drive timelines and risk management across studies.

The role requires expert leadership in CRO/vendor oversight, cross-functional collaboration, and the ability to work in a fast-paced, small company environment. Domestic travel up to 20% is expected.