Rare-Disease CAR-T Scientist: Precision T-Cell Engineer

Zenith LifeScience; Gaithersburg (MD); On-site; USD 85,000 - 125,000; Full time

Job summary

Zenith LifeScience seeks a Scientist to support rare disease CAR-T programs, executing experiments aligned to rare disease biology with safety and regulatory considerations. The role emphasizes precision, data integrity, and clear communication under defined project frameworks.

The Scientist conducts pre-designed experiments, including CAR-T related validation and data delivery, while collaborating with senior team members to refine experimental direction and ensure high-quality results.

Qualifications

• Bachelor degree with relevant experience in Immunology, Cell Biology, Bioengineering, or related field.
• Hands-on experience with CAR-T cell therapy or engineered T cell platforms.
• Demonstrated expertise in lentiviral vector production and associated QC assays.
• Strong practical experience with primary T cell culture and manipulation.
• Working knowledge of flow cytometry and functional T cell assays.
• Ability to work independently while following established protocols.

Responsibilities

• Execute pre-designed experimental plans for CAR-T cell engineering and validation
• Perform high-throughput lentiviral production and QC following established workflows, escalating issues as needed
• Conduct CAR validation and T-cell functional assays with guidance on experimental objectives
• Maintain accurate, traceable, and timely experimental documentation in electronic lab notebooks
• Communicate results clearly and proactively, including deviations, challenges, or unexpected findings
• Contribute to team troubleshooting discussions
• Work independently on assigned tasks while seeking input on experimental design changes
• Adhere strictly to Company data integrity, safety, and compliance standards

Skills

CAR-T cell therapy

Lentiviral vector production

Primary T cell culture

Flow cytometry

Independent work

Education

Bachelor's degree in Immunology/Cell Biology/Bioengineering

Tools

Flow cytometer

Electronic Lab Notebooks

Job description

Zenith LifeScience seeks a Scientist to support rare disease CAR-T programs, executing experiments aligned to rare disease biology with safety and regulatory considerations. The role emphasizes precision, data integrity, and clear communication under defined project frameworks.

The Scientist conducts pre-designed experiments, including CAR-T related validation and data delivery, while collaborating with senior team members to refine experimental direction and ensure high-quality results.