Radiochemist

US132 Guidehouse Digital, LLC; Bethesda (MD); On-site; USD 74,000 - 124,000; Full time

Benefits offered by this job

Medical, Rx, Dental & Vision Insurance

401(k) Retirement Plan

Parental Leave

Tuition Reimbursement

Job summary

Guidehouse is seeking an experienced radiochemist to support the development of PET imaging probes at our Bethesda, MD site. This full-time role involves managing routine radiotracer production, documenting processes, and collaborating with multidisciplinary teams while adhering to GMP and safety standards.

The candidate will synthesize, purify, and characterize 18F- and 89Zr-labeled probes, optimize radiolabeling methods, and help transition promising tracers to GMP production.

Qualifications

• Master’s degree; Minimum of three (3) years radiochemistry experience.
• Synthesis of PET imaging probes, especially 18F and 89Zr.
• Experience with GMP radiopharmaceutical production.
• Background in radiochemistry & analytical chemistry.

Responsibilities

• Manage routine production of PET radiotracers with thorough documentation.
• Synthesize, purify, and characterize PET imaging probes for preclinical/clinical research.
• Develop and optimize radiolabeling methods for new imaging probes.
• Produce tracers and transition promising radiotracers to GMP production.
• Collaborate with multidisciplinary teams to design and deliver imaging probes.
• Adhere to GMP, radiation safety, and institutional standards.

Skills

Radiochemistry

PET imaging probes

Automated synthesis platforms

GMP radiopharmaceutical production

Analytical chemistry

Public Trust clearance

Technical documentation

Education

Master's degree

Tools

GE TRACERlab

Trasis AllinOne

Job description

Job Family: Scientist Travel Required: None Clearance Required: Ability to Obtain Public Trust

What You Will Do

We are currently searching for an experienced radiochemist to support the development of specialized molecular imaging probes in support of the NIH. This full time position is located in Bethesda, MD.

• Manage the routine production of PET radiotracers, including maintaining thorough and accurate production documentation.
• Synthesize, purify, and characterize novel PET imaging probes to support preclinical and clinical research programs.
• Develop and optimize radiolabeling methods for new imaging probes.
• Produce tracers to support preclinical and clinical research and transition promising radiotracers from research-scale synthesis to GMP-compliant production when appropriate.
• Develop, optimize, validate, and troubleshoot radiolabeling methods for emerging molecular imaging agents and translational research applications.
• Collaborate with multidisciplinary teams to design, produce, and deliver novel molecular imaging probes.
• Adhere to GMP, radiation safety, laboratory safety, and institutional quality standards while working with radioactive materials and radiopharmaceutical production systems.
• Analyze experimental data, prepare technical reports, and communicate findings through written documentation, presentations, and scientific discussions.

What You Will Need

• Master’s degree Minimum of THREE (3) years of radiochemistry experience.
• Demonstrated expertise in the synthesis of novel positron emission tomography (PET) imaging probes, particularly those labeled with fluorine-18 (18F) and zirconium-89 (89Zr).
• Experience with automated synthesis platforms including GE TRACERlab and Trasis AllinOne modules is highly desirable.
• Experience with Good Manufacturing Practice (GMP) radiopharmaceutical production.
• A strong background in radiochemistry and analytical chemistry.
• Must be able to obtain and maintain a Federal or DoD Public Trust.
• Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse.
• Candidates with an active Public Trust or existing suitability are preferred.

What Would Be Nice To Have

• PhD preferred.
• Excellent problem‑solving skills and the ability to work effectively in a collaborative, service‑oriented research environment.
• Strong written and verbal communication skills.
• Able to work independently and in a team setting.
• Outstanding interpersonal and time management skills.
• Demonstrated experience in staff training and mentoring.

The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace. Benefits include:

• Medical, Rx, Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

Position may be eligible for a discretionary variable incentive bonus.

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [e-mail]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation. All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [e-mail]. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse.

Guidehouse is a global AI-led professional services firm delivering advisory, technology, and managed services to the commercial and government sectors. With an integrated business technology approach, Guidehouse drives efficiency and resilience in the healthcare, financial services, energy, infrastructure, and national security markets. Built to help clients across industries outwit complexity, the firm brings together approximately 18,000 professionals to achieve lasting impact and shape a meaningful future. guidehouse.com