Research Scientist

US132 Guidehouse Digital, LLC; Bethesda (MD); On-site; USD 98,000 - 163,000; Full time

Benefits offered by this job

Medical

Dental & Vision

401(k)

Holidays

Parental Leave

Tuition Reimbursement

EAP

Transit Benefits

Job summary

Guidehouse Digital, LLC is seeking a Research Scientist in Bethesda, MD to support NIH-related objectives. The role involves immunology and molecular biology work with human and animal cells, sequencing, and data analyses, plus presenting findings at meetings.

You will collaborate with cores, maintain mouse lines, and help prepare documents for scientific activities. The candidate should have a PhD/MD or equivalent and at least six years of research experience, with strong skills in molecular

Qualifications

• Ph.D. or M.D. or other doctoral degree in science, medicine, or related field.
• Six years of research experience in science, medicine, or related fields.
• Extensive experience in molecular biology, biochemistry, and immunology research.
• Experience generating knockout mice and working with mice models.
• Experience with next generation sequencing methods (RNA-seq, etc.).
• Experience with flow cytometry, immunohistochemistry, and related techniques.

Responsibilities

• Perform immunology and molecular biology techniques with cells/tissues.
• Carry out biochemical assays, Western blotting, and related analyses.
• Work with sequencing, mass spectrometry, flow cytometry cores.
• Maintain mouse lines, breed and genotype as needed.
• Present research at national and international meetings.
• Draft and edit papers, posters, and manuscripts.
• Serve as scientific consultant and collaborator for fellows.

Skills

Molecular biology

Biochemistry

Immunology

Mouse models

Next-gen sequencing

ChIP

qPCR

Flow cytometry

Immunohistochemistry

Cell culture

Education

PhD or MD or equivalent doctoral degree

Tools

Mass spectrometry

Sequencing equipment

Microsoft Office

PowerPoint

Job description

Job Family: Scientist Travel Required: Up to 10% Clearance Required: Ability to Obtain Public Trust

What You Will Do:

We are currently searching for a Research Scientist.

This role will independently provide support services to satisfy the overall operational objectives of the National Heart, Lung, and Blood Institute.

The primary objective is to provide services and deliverables through performance of support services.

This is a full-time opportunity located in Bethesda, MD.

Perform a wide array of immunology and molecular biological techniques with animal and human cells/tissues.

Perform a variety of biochemical assays, immuno-precipitations, polyacrylamide gel electrophoresis and western blotting.

Perform a range of next generation sequencing techniques, including for transcriptomics and epigenetic analyses.

Perform immunofluorescence staining and functional analyses of tissue samples.

Work with the sequencing, mass spectrometry, flow cytometry, and other cores as needed.

Maintain mouse lines (breeding, genotyping).

Present research at international and national research meetings.

Conduct and help direct independent research projects of high priority for the laboratory.

Assist the Lab Chief in the creating/preparing documents required by the Lab Chief’s scientific activities (e.g., CRADAs, Material Transfer Agreements, Patent Applications, Animal Protocols, BSC review).

Review, edit, and write drafts of papers, posters and manuscripts produced within the laboratory for consistency of the research agenda, adherence to any applicable scientific policies, and clarity of presentation of data and other scientific information.

Act as a scientific consultant, technical expert, and collaborator for IRTA fellows, Visiting Fellows, and others in the lab as needed.

What You Will Need:

• Ph.D. or M.D. or other appropriate doctoral degree in science, medicine, or related field
• Minimum of SIX (6) years of research experience in science, medicine, or related fields.
• Extensive experience in molecular biology, biochemistry, and immunology research, including experience in immune cell development and function.
• Experience generating knockout mice, conditional knockout mice, and extensive experience working with mice/mouse models.
• Extensive experience related to next generation sequencing methods and analyses (e.g., RNA-seq, scRNA-seq, ChIP-seq, ATAC-seq, Hi-C, HiChIP, PCA, UMAP, tSNE).
• Experience with advanced molecular biology techniques (e.g., ChIP, co-IP, advanced cloning techniques, western blotting, Northern blotting, Southern blotting, Q-PCR).
• Experience with flow cytometry, immunohistochemistry, and metabolomics.
• Extensive experience in cell culture and/or extensive knowledge of cell biology.
• Ability to manage and coordinate high-priority short- and long-term projects and studies in a fast-paced environment.

What Would Be Nice To Have:

• Previous experience with NIH preferred.
• Proficient in Microsoft Office and PowerPoint

The annual salary range for this position is $98,000.00-$163,000.00.

What We Offer:

• Medical
• Rx
• Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account
• Health Care & Dependent Care
• Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement
• Personal Development
• Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation. Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [e-mail]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation. All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [e-mail]. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse.

Guidehouse is a global AI-led professional services firm delivering advisory, technology, and managed services to the commercial and government sectors. With an integrated business technology approach, Guidehouse drives efficiency and resilience in the healthcare, financial services, energy, infrastructure, and national security markets. Built to help clients across industries outwit complexity, the firm brings together approximately 18,000 professionals to achieve lasting impact and shape a meaningful future. guidehouse.com