Radiochemist

Guidehouse; Bethesda (MD); On-site; USD 74,000 - 124,000; Full time

Benefits offered by this job

Health Insurance

401(k) Plan

Parental Leave

Tuition Reimbursement

Job summary

Guidehouse in Bethesda, MD is seeking an experienced radiochemist to support the development of PET imaging probes for NIH programs. You will manage routine production of radiotracers and maintain thorough production documentation.

You will synthesize, purify, and characterize novel PET probes, optimize radiolabeling methods for 18F and 89Zr, and transition promising tracers to GMP‑compliant production. Collaborative, safety‑driven work with GMP and analytical chemistry, reporting findings

Qualifications

• Minimum of 3 years of radiochemistry experience.
• Experience synthesizing PET imaging probes labeled with 18F and 89Zr.
• Experience with GMP radiopharmaceutical production.
• Strong background in radiochemistry and analytical chemistry.
• Must be able to obtain and maintain Public Trust.

Responsibilities

• Manage routine production of PET radiotracers with documentation.
• Synthesize, purify, and characterize novel PET probes.
• Develop and optimize radiolabeling methods for imaging probes.
• Produce tracers and transition promising radiotracers to GMP production.
• Collaborate with multidisciplinary teams and ensure GMP/safety compliance.

Skills

Radiochemistry

18F labeling

89Zr labeling

Analytical chemistry

Technical writing

Collaboration

Education

Master’s degree

PhD preferred

Tools

GE TRACERlab

Trasis AllinOne

Job description

Job Family:ScientistTravel Required:NoneClearance Required:Ability to Obtain Public TrustWhat You Will Do:We are currently searching for an experienced radiochemist to support the development of specialized molecular imaging probes in support of the NIH. This full time position is located in Bethesda, MD.Manage the routine production of PET radiotracers, including maintaining thorough and accurate production documentation.Synthesize, purify, and characterize novel PET imaging probes to support preclinical and clinical research programs.Develop and optimize radiolabeling methods for new imaging probes.Produce tracers to support preclinical and clinical research and transition promising radiotracers from research-scale synthesis to GMP-compliant production when appropriate.Develop, optimize, validate, and troubleshoot radiolabeling methods for emerging molecular imaging agents and translational research applications.Collaborate with multidisciplinary teams to design, produce, and deliver novel molecular imaging probes.Adhere to GMP, radiation safety, laboratory safety, and institutional quality standards while working with radioactive materials and radiopharmaceutical production systems.Analyze experimental data, prepare technical reports, and communicate findings through written documentation, presentations, and scientific discussions.What You Will Need:Master’s degreeMinimum of THREE (3) years of radiochemistry experience.Demonstrated expertise in the synthesis of novel positron emission tomography (PET) imaging probes, particularly those labeled with fluorine-18 (18F) and zirconium-89 (89Zr).Experience with automated synthesis platforms including GE TRACERlab and Trasis AllinOne modules is highly desirable.Experience with Good Manufacturing Practice (GMP) radiopharmaceutical production.A strong background in radiochemistry and analytical chemistry.Must be able to obtain and maintain a Federal or DoD Public Trust. Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse. Candidates with an active Public Trust or existing suitability are preferred.What Would Be Nice To Have:PhD preferred.Excellent problem-solving skills and the ability to work effectively in a collaborative, service-oriented research environment.Strong written and verbal communication skills.Able to work independently and in a team setting.Outstanding interpersonal and time management skills.Demonstrated experience in staff training and mentoring.The annual salary range for this position is $74,000.00-$124,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.What We Offer:Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.Benefits include:Medical, Rx, Dental & Vision InsurancePersonal and Family Sick Time & Company Paid HolidaysParental Leave401(k) Retirement PlanGroup Term Life and Travel AssistanceVoluntary Life and AD&D InsuranceHealth Savings Account, Health Care & Dependent Care Flexible Spending AccountsTransit and Parking Commuter BenefitsShort-Term & Long-Term DisabilityTuition Reimbursement, Personal Development, Certifications & Learning OpportunitiesEmployee Referral ProgramCorporate Sponsored Events & Community OutreachCare.com annual membershipEmployee Assistance ProgramSupplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)Position may be eligible for a discretionary variable incentive bonusAbout GuidehouseGuidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [e-mail]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [e-mail]. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact [e-mail]. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.