Purification Scientist II: Antisense/siRNA & Peptide

Biogen, Inc.; Cambridge (MA); On-site; USD 117,000 - 157,000; Full time

Benefits offered by this job

Medical Insurance

Dental Vision

Wellness reimbursement

Paid time off & holidays

401(k) plan

Stock purchase plan

Tuition reimbursement

Job summary

Biogen is seeking a Scientist II to join the Technical Development team in Cambridge, MA, focusing on oligonucleotide and peptide purification. You will design, develop, and scale robust purification processes from early development to commercial, using data-driven DoE to define control strategies and enable tech transfers into GMP manufacturing.

You will contribute to regulatory documentation and collaborate with multidisciplinary teams to deliver scalable, high-quality processes that support

Qualifications

• Ph.D. degree in chemical engineering, chemistry, or a related science with 0-3 years of experience
• Master’s degree in chemical engineering, chemistry, or a related science with 4+ years of experience in pharmaceutical or biotech settings
• Bachelor’s degree in chemical engineering, chemistry, or a related science with 6+ years of relevant experience in pharmaceutical or biotech settings
• Experience in purification process development, preferably in an industrial environment
• Strong analytical skills and statistical analysis expertise
• Proficiency in technical writing and presenting technical data

Responsibilities

• Design, develop, and scale purification processes across development stages (early development through commercial)
• Apply data-driven approaches (e.g., DoE) to characterize processes and define robust control strategies
• Lead or support technology transfer of processes into GMP manufacturing
• Troubleshoot process challenges and drive continuous improvement in process performance
• Collaborate with Manufacturing, Analytical, Quality, Non-Clinical, and Regulatory teams to enable program advancement
• Author technical reports and contribute to CMC sections of regulatory filings and respond to agency questions

Skills

Analytical skills

Statistical analysis

Technical writing

DoE design of experiments

Education

Ph.D. in chemical engineering/chemistry

Master’s in chemical engineering/chemistry

Bachelor’s in chemical engineering/chemistry

Job description

Biogen is seeking a Scientist II to join the Technical Development team in Cambridge, MA, focusing on oligonucleotide and peptide purification. You will design, develop, and scale robust purification processes from early development to commercial, using data-driven DoE to define control strategies and enable tech transfers into GMP manufacturing.

You will contribute to regulatory documentation and collaborate with multidisciplinary teams to deliver scalable, high-quality processes that support