Proteomics Mass Spec Research – Intact Protein Analysis

Cold Spring Harbor Laboratory; Cold Spring Harbor (NY); On-site; USD 50,000 - 83,000; Full time

Job summary

Cold Spring Harbor Laboratory invites applications for a Research Associate specializing in intact protein LC-ESI-MS analyses and measurements of chemically modified proteins and peptides. The Mass Spectrometry Shared Resource collaborates with internal groups and external partners to push proteomic and metabolomic methods forward.

The role covers sample processing, MS-based method development, and instrument maintenance, with active participation in meetings, seminars, and journal clubs,

Qualifications

• PhD in Analytical Chemistry is required.
• Demonstrable experience with mass spectrometry-based proteomics.
• High-resolution LC/MS experience is very important.

Responsibilities

• Perform sample preparation and analysis.
• Operate Orbitrap mass spectrometers and micro/nanoflow chromatographs.
• Perform data analysis and reporting for proteomics/metabolomics experiments.
• Contribute to development of novel proteomic/metabolomic methods.
• Implement and test new proteomic/metabolomic techniques.
• Assist with instrument maintenance and quality control procedures.
• Maintain and update written operative procedures and experimental protocols.
• Help maintain commonly used equipment and resolve minor equipment problems.

Skills

Mass spectrometry

Proteomics

Analytical chemistry

Education

PhD in Analytical Chemistry

Tools

Orbitrap mass spectrometers

Micro/nanoflow chromatographers

Job description

Cold Spring Harbor Laboratory invites applications for a Research Associate specializing in intact protein LC-ESI-MS analyses and measurements of chemically modified proteins and peptides. The Mass Spectrometry Shared Resource collaborates with internal groups and external partners to push proteomic and metabolomic methods forward.

The role covers sample processing, MS-based method development, and instrument maintenance, with active participation in meetings, seminars, and journal clubs,