Protein Purification Scientist II – Chromatography Pro

Actalent; Carlsbad (CA); On-site; USD 41,000 - 51,000; Full time

Job summary

Actalent seeks a Scientist II, Protein Purification in Carlsbad, CA to perform hands-on purification in a controlled manufacturing lab. You will run chromatographic purification processes, operate ÄKTA/UNICORN and Bio-Rad NGC systems, prepare buffers, and document activities supporting SOPs and batch records.

The role involves troubleshooting routinely, maintaining records, and contributing to process improvement, validation, and investigations in a fast-paced manufacturing environment.

Qualifications

• Bachelor's degree in Biology, Chemistry, Biochemistry or related discipline.
• 3+ years of protein purification experience.
• Hands-on experience independently executing protein purification workflows.
• Strong understanding of protein chemistry and chromatography.
• Ability to work independently within established procedures.
• Strong troubleshooting and problem-solving skills.

Responsibilities

• Execute protein purification workflows independently using chromatography modes (affinity, ion-exchange, size-exclusion, hydrophobic interaction).
• Operate FPLC purification systems, with preference for Cytiva ÄKTA systems using UNICORN or Bio-Rad NGC systems.
• Evaluate chromatograms and data to identify abnormal purification performance and troubleshoot issues.
• Document manufacturing activities and maintain batch and equipment records.
• Participate in process improvement, validation, qualification, and investigation activities.

Skills

Protein purification

Chromatography

FPLC systems

Troubleshooting

Documentation

Independent work

Education

Bachelor's degree in Biology, Chemistry, Biochemistry

Tools

ÄKTA/UNICORN

Bio-Rad NGC

Job description

Actalent seeks a Scientist II, Protein Purification in Carlsbad, CA to perform hands-on purification in a controlled manufacturing lab. You will run chromatographic purification processes, operate ÄKTA/UNICORN and Bio-Rad NGC systems, prepare buffers, and document activities supporting SOPs and batch records.

The role involves troubleshooting routinely, maintaining records, and contributing to process improvement, validation, and investigations in a fast-paced manufacturing environment.