Production Research Associate I: High-Throughput Biotech

BigHat Biosciences; San Mateo (CA); On-site; USD 75,000 - 88,000; Full time

Job summary

BigHat Biosciences in San Mateo, CA, is seeking a Research Associate I, Production to operate automated and manual high-throughput processes for antibody production and molecular characterization. You will contribute to scaling the platform and data generation, while supporting in-house reagent production and SOP development.

The role requires a BS in Biology or Chemistry with 1+ year of industry experience, hands-on lab skills, and the ability to manage multiple projects in a dynamic startup.

Qualifications

• BS in Biology or Chemistry with 1+ year of industry experience.
• Experience in process execution, laboratory method development, optimization, and troubleshooting.
• Ability and willingness to work specific workday schedules as needed (e.g., 7AM–3PM or 10AM–6PM).
• Hands-on experience with automated liquid handlers (Hamilton, OpenTrons, Tecan, Agilent); LIMS experience is a plus.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously in a dynamic start-up environment.
• Strong interpersonal and communication skills within a multidisciplinary team.
• Excellent record-keeping abilities to document experimental work and data.
• Nice-to-haves: barcoding, inventory tracking, and Google Workspace tools.

Responsibilities

• Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
• Contribute to scaling up BigHat’s platform and production‑grade data generation.
• Support Platform Reagents & Assay Support (PRAS) by contributing to in-house reagent manufacturing.
• Execute experiments to optimize performance efficiency of BigHat’s platform.
• Keep detailed records of all experiments using BigHat’s documentation tools and communicate results clearly.
• Collaborate on creating laboratory SOPs for sample processing.
• Collaborate to identify and implement process and operational improvements to production workflows and lab systems.
• Operate automated liquid handlers and analytical instruments to ensure efficient lab operations.

Skills

Process execution

Laboratory method development

Optimization

Troubleshooting

Flexible schedule

Molecular biology

Lab practices

Time management

Multitasking

Communication

Record-keeping

Inventory tracking

Barcoding

Google Workspace

Education

BS in Biology or Chemistry

Tools

Hamilton

OpenTrons

Tecan

Agilent

LIMS

Job description

BigHat Biosciences in San Mateo, CA, is seeking a Research Associate I, Production to operate automated and manual high-throughput processes for antibody production and molecular characterization. You will contribute to scaling the platform and data generation, while supporting in-house reagent production and SOP development.

The role requires a BS in Biology or Chemistry with 1+ year of industry experience, hands-on lab skills, and the ability to manage multiple projects in a dynamic startup.