Research Associate II, Production

BigHat Biosciences; San Mateo (CA); On-site; USD 88,000 - 100,000; Full time

Benefits offered by this job

Bonus potential

Stock options

Benefits package

Job summary

BigHat Biosciences is seeking a driven Research Associate II, Production in San Mateo, CA to support its high-throughput automated platform for antibody production and deep molecular characterization.

You will perform automated and manual processing, help scale the platform, and contribute to reagent manufacturing while maintaining thorough records and collaborating to improve production workflows.

Qualifications

• BS in Biology or Chemistry, with 2+ years of industry experience.
• Experience in process execution, laboratory method development, optimization, and troubleshooting.
• Ability to work specific workday schedules (e.g., 7AM–3PM or 10AM–6PM).
• Hands-on experience with automated liquid handlers; familiarity with LIMS is a plus.

Responsibilities

• Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
• Contribute to the scaling up of BigHat’s platform and production-grade data generation.
• Support PRAS reagent manufacture efforts.
• Execute experiments to optimize performance efficiency of the platform.
• Keep detailed records using BigHat documentation tools and communicate results clearly.
• Collaborate on SOPs for sample processing.

Skills

Biology or Chemistry degree

2+ years industry experience

Process execution

Molecular biology

Method development

Optimization

Troubleshooting

Automation (liquid handling)

LIMS experience

Time management

Interpersonal communication

Google Workspace tools

Education

BS in Biology or Chemistry

Tools

Hamilton

OpenTrons

Tecan

Agilent systems

LIMS

Job description

Department: Lab Science
Location: San Mateo, CA

The role:

BigHat Biosciences is seeking a self-motivated individual for a Research Associate II, Production role to power our high-throughput, automated platform for antibody production and deep molecular characterization.

Key Responsibilities

• Perform automated and manual high-throughput processing on the BigHat platform, including DNA preparation, protein expression, and protein characterization.
• Contribute to the scaling up of BigHat’s platform and production-grade data generation.
• Support BigHat’s Platform Reagents & Assay Support (PRAS) function by contributing to in-house reagent manufacturing efforts.
• Execute experiments to optimize the performance efficiency of BigHat’s platform.
• Keep a detailed record of all experiments using BigHat’s documentation tools, and clearly communicate results and challenges.
• Collaborate on the creation of laboratory standard operating procedures (SOPs) for sample processing.
• Collaborate closely with BigHat team members to identify, design, and implement critical process and operational improvements to production workflows and laboratory systems.
• Operate automated liquid handlers and analytical instruments to ensure all lab and platform operations run efficiently.

Skills Knowledge And Expertise

• BS in Biology or Chemistry, with 2+ year(s) of industry experience
• Experience in process execution, laboratory method development, optimization, and troubleshooting.
• Ability and willingness to work specific workday schedules as needed, for example 7AM to 3PM or 10AM to 6PM.
• Hands-on experience with, or interest in, automated liquid handlers (e.g. Hamilton, OpenTrons, Tecan, Agilent systems). Experience with LIMS is a nice-to-have.
• Experience with molecular biology techniques and general lab practices.
• Efficient time management and ability to work on several projects simultaneously, in a dynamic start-up environment.
• Strong interpersonal skills and ability to effectively communicate with members of a multidisciplinary team.
• Excellent record keeping abilities to document experimental work and analytical data.
• Nice-to-haves include previous experience working with barcoding systems, inventory tracking, and experience with Google Workspace tools (Docs, Sheets, Slides, etc.)

Total Rewards

• The salary estimated for this position is $88,000 - $100,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.