Process Sciences Engineer, Gene Therapy (AAV Upstream)

Encoded Therapeutics; Morrisville (NC); On-site; USD 110,000 - 160,000; Full time

Benefits offered by this job

Stock options

PTO & holidays

Parental Leave

Pre-tax medical and dependent care

Wellness Resources

Professional development

Job summary

Encoded Therapeutics is hiring an Engineer, Process Sciences to advance genetic medicine programs, including AAV production and plasmid manufacturing. The role offers cross-functional collaboration across pre-clinical and clinical stages and emphasizes cGMP-compliant process development.

You will support technology transfer, process optimization, and manufacturing at internal and external sites, contributing to pipeline projects and ensuring readiness for clinical and potentially commercial

Qualifications

• Extensive knowledge of modern laboratory procedures and cGMP is required.
• Independently design, execute, and analyze small-scale cell culture studies (cell expansion, single-use bioreactors, harvest/clarification).
• 3+ years of industry experience; MSAT/PD/Process Sciences experience preferred.
• Strong collaboration and ability to meet project timelines.

Responsibilities

• Design, execute, and analyze small-scale studies to support two at-scale products and Encoded’s pipeline.
• Serve as engineer for pre-clinical and clinical manufacturing for AAV projects and plasmid manufacturing.
• Facilitate tech transfer of manufacturing processes to GMP and non-GMP sites.
• Provide on-site support of GMP manufacturing at internal and external sites.
• Develop tools/templates to support tech transfer business processes.

Skills

cGMP knowledge

cell culture

team player

planning & multitasking

verbal & written communication

Education

B.S. or M.S. in biochemical engineering, chemical engineering, biological sciences, virology, molecular biology, or biochemistry

Job description

Encoded Therapeutics is hiring an Engineer, Process Sciences to advance genetic medicine programs, including AAV production and plasmid manufacturing. The role offers cross-functional collaboration across pre-clinical and clinical stages and emphasizes cGMP-compliant process development.

You will support technology transfer, process optimization, and manufacturing at internal and external sites, contributing to pipeline projects and ensuring readiness for clinical and potentially commercial