Manager, Manufacturing Science & Technology

Scorpion Therapeutics; United States; Remote; USD 150,000 - 190,000; Full time

Job summary

Scorpion Therapeutics seeks a Manager, Manufacturing Science & Technology to support development and commercialization of rAAV-based gene therapies. You will oversee tech transfer from process development to GMP manufacturing, including validation, batch review, deviation management, and supply chain risk mitigation.

The role requires hands-on GMP experience with upstream suspension cell culture (HEK293), strong regulatory knowledge for gene therapy, and excellent communication.

Qualifications

• Bachelor's degree in biotech, chemical, or pharmaceutical engineering.
• 5+ years experience in biotech/pharma manufacturing.
• Hands-on GMP manufacturing experience with upstream suspension cell culture.
• Knowledge of gene therapy regulatory requirements.
• Strong communication and ability to work independently with travel up to 40%.

Responsibilities

• Oversee end-to-end technology transfer from process development to GMP manufacturing, including validation, batch review, monitoring, deviations, change control, and supply chain risk mitigation.
• Act as a technical interface between Process Development, CMC, and manufacturing teams.

Skills

GMP manufacturing

cell culture

regulatory knowledge

communication skills

remote work travel

Education

Bachelor's degree

Tools

HEK293

Job description

Role:

Manager, Manufacturing Science & Technology, supporting the development and commercialization of rAAV-based gene therapies.

Responsibilities:

• oversee end-to-end technology transfer from process development to GMP manufacturing, including process validation, batch record review, process monitoring, deviation management, change control, and supply chain risk mitigation
• act as a technical interface between Process Development, CMC, and manufacturing teams.

Requirements:

• Bachelor's degree with 5+ years in biotech, chemical, or pharmaceutical engineering;
• hands-on GMP manufacturing experience, particularly with upstream suspension cell culture (HEK293) and ultracentrifugation;
• strong knowledge of gene therapy regulatory requirements;
• excellent communication skills;
• ability to work independently in a remote setting with occasional global travel (up to 40%).

Preferred:

drug product fill process expertise.

HighValue:

gene therapy (AAV vectors), process transfer, GMP manufacturing, early to late phase development, cross-functional collaboration, remote work with travel.