Principal Statistical Methodology Scientist - Strategy & Innovation

F. Hoffmann-La Roche AG; South San Francisco (CA); On-site; USD 185,000 - 344,000; Full time

Job summary

Genentech is seeking a Principal Statistical Methodology Data Scientist in California to advance fit-for-purpose statistics across programs and portfolios. You will partner with study teams and cross-functional stakeholders to design innovative methods and prototype solutions, including estimand frameworks and trial simulations.

You will mentor junior staff, contribute to internal standards, publish educational materials, and help drive scalable analytics adoption across the organization.

Qualifications

• PhD in Biostatistics, Statistics, Data Science, Computer Science, or related field.
• 6+ years of experience designing and applying advanced analytics to complex biomedical data in clinical trials.
• Deep expertise in statistical computing and advanced modeling.
• Recognized as a technical expert and thought partner within the organization or field.
• Experience mentoring others and contributing to internal standards, strategy, or capability development.
• Ability to collaborate respectfully across a global team.

Responsibilities

• Serve as methodological thought partner to study teams.
• Lead development and institutionalization of methodologies for trial and portfolio decisions.
• Shape cross-functional understanding through consultation, publications, and education.
• Anticipate regulatory trends and integrate methodologies into internal practices.
• Mentor junior staff and influence strategic direction.

Skills

Advanced analytics

Statistical computing

Modeling expertise

Mentoring others

Cross-functional collaboration

Education

PhD in Biostatistics/Statistics/Data Science/CS

Job description

Genentech is seeking a Principal Statistical Methodology Data Scientist in California to advance fit-for-purpose statistics across programs and portfolios. You will partner with study teams and cross-functional stakeholders to design innovative methods and prototype solutions, including estimand frameworks and trial simulations.

You will mentor junior staff, contribute to internal standards, publish educational materials, and help drive scalable analytics adoption across the organization.