Principal Scientist – Translational Cell Therapy

Bristol-Myers Squibb; Seattle (WA); On-site; USD 152,000 - 185,000; Full time

Benefits offered by this job

Flexible Time Off

Comprehensive benefits

Stock opportunities

Paid holidays

Job summary

Bristol Myers Squibb's Cellular Therapy Translational Biology Research group in Seattle, WA, seeks an experienced Principal Scientist to lead laboratory-based translational studies across oncology and autoimmune indications. You will design experiments, generate data to support regulatory decisions, collaborate across disciplines, and mentor junior scientists in a fast-paced, mission-driven environment.

Strong communication and scientific publishing skills are essential as you contribute to IND

Qualifications

• Bachelor’s/Master’s/PhD with 4+ years experience in Life Sciences.
• Experience leading lab-based translational biology projects.
• Strong analytical and communication skills.

Responsibilities

• Develop and lead focused research projects with independent design and interpretation.
• Direct and execute lab research to characterize product function and inform clinical interpretation and indication strategy.
• Lead non-clinical data packages to support regulatory submissions and indication expansion for cell therapy programs.
• Contribute to biomarker strategy and patient stratification approaches to guide clinical decision-making.
• Lead the development, design, and optimization of novel in vitro assays and models to advance translational research objectives.
• Investigate the impact of manufacturing and process changes on product functional comparability to support regulatory filings and process decisions.
• Represent Translational Biology on cross-functional program teams spanning Discovery, Clinical, Regulatory, and Manufacturing.
• Contribute to the writing of non-clinical pharmacology study reports, investigator brochures, IND applications, regulatory annual reports, and other regulatory documents when appropriate.
• Coordinate external collaborations and/or be the subject matter expert.
• Act as a technical point of contact and mentor to junior scientists.
• Present data and analysis at cross-functional program meetings; contribute to conference abstracts, manuscripts, and patent disclosures.
• Contribute to lab stewardship initiatives to support productivity, safety, and inspection readiness.

Skills

Experimental design

Biomarker analysis

Flow cytometry

Independent research

Cell therapy

Collaboration

Education

Bachelor’s Degree

Master’s Degree

Ph.D. or equivalent

Tools

Incucyte

JMP

GraphPad Prism

Job description

Bristol Myers Squibb's Cellular Therapy Translational Biology Research group in Seattle, WA, seeks an experienced Principal Scientist to lead laboratory-based translational studies across oncology and autoimmune indications. You will design experiments, generate data to support regulatory decisions, collaborate across disciplines, and mentor junior scientists in a fast-paced, mission-driven environment.

Strong communication and scientific publishing skills are essential as you contribute to IND