Principal Scientist: Optimization, Simulation & Digital Twin

NCSL International

Northern (KY)

Hybrid

USD 117,000 - 201,000

Full time

5 days ago

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Job summary

Johnson & Johnson Innovative Medicine seeks a hands-on Principal Scientist to design and scale optimization, simulation, and digital-twin capabilities across Therapeutics Development & Supply. You will translate complex processes into rigorous models and deploy decision-support tools in enterprise workflows.

The role combines deep expertise in operations research with software engineering disciplines, partnering with data engineering, product, and platform teams to drive portfolio planning and

Qualifications

Advanced degree in quantitative field as listed in qualifications.
Demonstrated depth in multiple OR/IO methods and strong Python skills.

Responsibilities

Formulate and solve optimization problems for portfolio prioritization and resource scheduling.
Develop models and simulations to represent complex operations and decision workflows.
Deliver scalable modeling workflows and decision-support products using Python and modern computing tools.
Collaborate with cross-functional teams to integrate models with enterprise data and workflows.

Skills

Python

Optimization

Simulation

Digital Twin

Modeling

Leadership

Education

Operations Research

Industrial Engineering

Applied Mathematics

Tools

Pyomo

Gurobi

CPLEX

OR-Tools

SimPy

AnyLogic

Simio

Arena

Job description

The role combines deep expertise in operations research with software engineering disciplines, partnering with data engineering, product, and platform teams to drive portfolio planning and

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