Principal LC-MS Bioprocess Systems Architect

Waters Corporation; Milford (DE); On-site; USD 120,000 - 190,000; Full time

Job summary

Waters Corporation is seeking a senior bioprocess LC/MS systems engineer to define and deliver next-generation analytical technologies. You will work across engineering, research, and customer teams to translate market needs into robust, deployed solutions, both in-house and on-site with customers.

Responsibilities include leading architecture, integration, verification, and transitioning from development to real-world applications, with ~40% travel to customer sites.

Qualifications

• Degree in Physics, Chemistry, or related field.
• Experience leading development or integration of LC-MS systems.
• Ability to define requirements, architecture, and integration across hardware, software, and informatics.
• Strong problem-solving and diagnostic skills.
• Effective communication and stakeholder management across global teams.
• Hands-on experience with experimental systems, including setup, testing, and evaluation.

Responsibilities

• Lead design and delivery of bioprocess LC/MS solutions from concept to deployment.
• Own system requirements and architecture; provide technical leadership across cross-functional teams.
• Define and implement system integration and verification strategies for robust performance.
• Act as technical authority for designated systems; resolve complex challenges and drive design decisions.
• Drive evaluation and integration of new technologies; transition research into commercial products.
• Lead transition of systems from development to real-world use, including customer evaluations and on-site installation (≈40% travel).

Skills

System architecture

Cross-functional leadership

Problem solving

Communication

Hands-on testing

Education

Physics/Chemistry degree

Tools

LC-MS systems

Job description

Waters Corporation is seeking a senior bioprocess LC/MS systems engineer to define and deliver next-generation analytical technologies. You will work across engineering, research, and customer teams to translate market needs into robust, deployed solutions, both in-house and on-site with customers.

Responsibilities include leading architecture, integration, verification, and transitioning from development to real-world applications, with ~40% travel to customer sites.