Principal Investigator (MD/DO) - Cardiology Clinical Trials

Hawthorne Health; Springfield (MO); Hybrid; USD 138,000 - 344,000; Part time

Benefits offered by this job

1099 contractor

Job summary

Hawthorne Health is seeking an experienced Cardiology Principal Investigator (MD/DO) for a part-time, 1099 role to lead Cardiology/Metabolic trials within our community-based site network. You will ensure protocol adherence, patient safety, and high-quality data collection.

Role requires on-site presence 1–4 times per month with remote oversight (3–5 hours weekly). Compensation ranges from $100 to $250 per hour, with terms flexible by experience and qualifications.

Qualifications

• MD/DO with leadership of at least three sponsor-initiated trials as PI/Sub-I.
• Current, unrestricted medical license.
• Board certification in Cardiology preferred.
• Strong knowledge of ICH-GCP guidelines and FDA regulations.

Responsibilities

• Document findings and contribute to trials, registries, or protocols.
• Oversee all aspects of trials at the site, ensuring protocol and regulatory compliance.
• Lead and supervise the clinical research team and training.
• Delegate duties to qualified personnel with proper oversight.
• Remote review of patient assessments to support enrollment decisions.
• Interpret laboratory results and diagnostic tests.
• Make medical decisions regarding participant care and safety.
• Ensure complete data collection and documentation.
• Communicate with sponsors, CROs, IRBs, and regulators.
• Manage IP accountability, storage, and administration per protocol.
• Participate in site initiation, monitoring, audits, and inspections.

Skills

Leadership

ICH-GCP knowledge

FDA regulations

English communication

Organizational skills

Study management

Education

MD/DO

Job description

About Us

Hawthorne Health is a leading community site network and home research visit solution provider, with 20+ sites and more than 2,000 research experienced healthcare professionals across the U.S. Hawthorne leverages convenient, trusted, healthcare locations, identified patient data, and intelligent technology to accelerate patient access, improve retention, and reduce study costs. By embedding high-quality research within local communities, Hawthorne makes clinical trials more accessible and convenient for patients. Our community-based model shortens timelines and helps bring better treatments to market, faster.

About the Role

Hawthorne Health is seeking an experienced Cardiology Principal investigator (MD/DO) for a part-time, 1099 role. Candidates should have prior experience as a PI or Sub-I on sponsor-initiated clinical trials. This role will lead Cardiology/Metabolic trials within our growing, community-based site network—built to make research efficient, patient-friendly, and investigator-supported.

$100 - $250 an hour

This is a 1099 independent contractor opportunity. Compensation may be flexible and adjusted based on experience and qualifications.

Responsibilities

• Accurately document findings and contribute to ongoing clinical trials, registries, or research protocols as applicable.
• Oversee and manage all aspects of clinical trials conducted at the research site, ensuring adherence to the study protocol, Good Clinical Practice (GCP), ICH guidelines, and all applicable regulatory requirements.
• Lead and supervise the clinical research team, including sub-investigators, study coordinators, and other site staff.
• Delegate study-related duties appropriately to qualified personnel and ensure proper training and oversight.
• Conduct remote review of patient assessments, including physical exams, medical histories, and eligibility screenings, to ensure appropriate participant enrollment.
• Review and interpret laboratory results, ECGs, and other diagnostic tests.
• Make critical medical decisions regarding participant care, adverse events, and protocol deviations.
• Ensure accurate, complete, and timely collection and documentation of all study data.
• Communicate effectively with sponsors, Contract Research Organizations (CROs), Institutional Review Boards (IRBs), and regulatory authorities.
• Manage investigational product accountability, storage, and administration according to protocol and with the help of the on-site IP team.
• Participate in site initiation visits, monitoring visits, audits, and inspections.
• Maintain continuous medical education and stay current with advancements in clinical research and relevant therapeutic areas.

Requirements

• Must be an MD with experience leading at least three sponsor initiated trials as a PI or Sub-I.
• Current, unrestricted medical license.
• Board certification in Cardiology preferred.
• Demonstrated in-depth knowledge of ICH-GCP guidelines, FDA regulations, and other relevant ethical and regulatory requirements for clinical research.
• Proven leadership and team management skills.
• Excellent clinical judgment and decision-making abilities.
• Strong verbal and written communication skills in English, with the ability to present complex information clearly and concisely.
• Exceptional organizational skills and meticulous attention to detail.
• Ability to manage multiple complex studies simultaneously and prioritize tasks effectively.
• Commitment to ethical conduct and patient safety.

Location

• This role requires on-site presence approximately 1-4 times per month for key visits (or more, depending on study needs), with additional oversight responsibilities performed remotely (approximately 3–5 hours per week).

Hawthorne Health is transforming the clinical trial landscape through an innovative site model that integrates research into community-based settings like local pharmacies. By meeting patients where they already receive care, we are improving access, strengthening trust, and driving more inclusive and efficient trials.

We welcome the opportunity to connect with individuals interested in being part of this evolving model.