MD/DO Consultant - Principal Investigator, Clinical Trials

Hawthorne Health, Inc.; McAllen (TX); Hybrid; USD 138,000 - 344,000; Part time

Job summary

Hawthorne Health is seeking a Principal Investigator (MD) for a 1099, part-time role to lead clinical investigations at our new McAllen, TX site. The PI will conduct remote oversight (3–5 hours/week) and be on-site ~1–4 times per month, within a 1.5-hour radius of the site.

The ideal candidate holds an MD with an unrestricted license, has PI experience on at least 3 sponsor-initiated trials, and is proficient in ICH-GCP and FDA regulations. Strong leadership and communication skills are required.

Qualifications

• PI experience on at least 3 sponsor-initiated clinical trials.
• MD degree from an accredited institution.
• Current, unrestricted medical license.
• Board certification in a relevant specialty preferred.
• Strong knowledge of ICH-GCP, FDA regulations, and ethical/regulatory requirements.

Responsibilities

• Accurately document findings and contribute to trials, registries, or research protocols.
• Oversee and manage all clinical trial activities at the site.
• Lead and supervise the clinical research team and delegate duties.
• Remote review of patient assessments to ensure proper enrollment.
• Communicate with sponsors, CROs, and IRBs; manage data collection and documentation.
• Ensure investigational product accountability and site visits compliance.
• Participate in initiation visits, monitoring visits, audits, and inspections.

Skills

English communication

Leadership

Clinical judgment

Attention to detail

Time management

Education

MD or equivalent

Medical license

Board certification preferred

Job description

About Us

Hawthorne Health is a leading community site network and home research visit solution provider, with 20+ sites and more than 2,000 research experienced healthcare professionals across the U.S. Hawthorne leverages convenient, trusted, healthcare locations, identified patient data, and intelligent technology to accelerate patient access, improve retention, and reduce study costs. By embedding high-quality research within local communities, Hawthorne makes clinical trials more accessible and convenient for patients. Our community-based model shortens timelines and helps bring better treatments to market, faster.

About the Role

Hawthorne Health is seeking an experienced, Principal Investigator MD on a 1099 contract opportunity to join our growing team and lead the investigation for our new site in McAllen, TX.

Responsibilities

• Accurately document findings and contribute to ongoing clinical trials, registries, or research protocols as applicable.
• Oversee and manage all aspects of clinical trials conducted at the research site, ensuring adherence to the study protocol, Good Clinical Practice (GCP), ICH guidelines, and all applicable regulatory requirements.
• Lead and supervise the clinical research team, including sub-investigators, study coordinators, and other site staff.
• Delegate study-related duties appropriately to qualified personnel and ensure proper training and oversight.
• Conduct remote review of patient assessments, including physical exams, medical histories, and eligibility screenings, to ensure appropriate participant enrollment.
• Review and interpret laboratory results, ECGs, and other diagnostic tests.
• Make critical medical decisions regarding participant care, adverse events, and protocol deviations.
• Ensure accurate, complete, and timely collection and documentation of all study data.
• Communicate effectively with sponsors, Contract Research Organizations (CROs), Institutional Review Boards (IRBs), and regulatory authorities.
• Manage investigational product accountability, storage, and administration according to protocol and with the help of the on-site IP team.
• Participate in site initiation visits, monitoring visits, audits, and inspections.
• Maintain continuous medical education and stay current with advancements in clinical research and relevant therapeutic areas.

Requirements

• Experience as a Principal Investigator on at least 3 sponsor initiated clinical trials.
• Medical Doctor (M.D. or equivalent) degree from an accredited institution.
• Current, unrestricted medical license.
• Board certification in a relevant specialty preferred.
• Demonstrated in-depth knowledge of ICH-GCP guidelines, FDA regulations, and other relevant ethical and regulatory requirements for clinical research.
• Proven leadership and team management skills.
• Excellent clinical judgment and decision-making abilities.
• Strong verbal and written communication skills in English, with the ability to present complex information clearly and concisely.
• Exceptional organizational skills and meticulous attention to detail.
• Ability to manage multiple complex studies simultaneously and prioritize tasks effectively.
• Commitment to ethical conduct and patient safety.

Location & Time Commitment

• 3-5 hours per week of remote clinical oversight.
• This position requires being on site in McAllen, TX ~1-4 times per month for key visits.
• PI will need to be located within 1.5 hours driving distance to the site.

$100 - $250 an hour

Position Type: Part-time, 1099 contract

Compensation: Hourly; rate negotiable based on experience

Hawthorne Health is transforming the clinical trial landscape through an innovative site model that integrates research into community-based settings like local pharmacies. By meeting patients where they already receive care, we are improving access, strengthening trust, and driving more inclusive and efficient trials.

We welcome the opportunity to connect with individuals interested in being part of this evolving mode