Principal Business Support Specialist

Immatics US, Inc.; Houston (TX); On-site; USD 70,000 - 100,000; Full time

Benefits offered by this job

Health, dental & vision insurance

4 weeks vacation (annual)

12 holidays

7 sick days

Company-paid life insurance

Disability insurance

401(k) with company match

Parental leave

Additional voluntary benefits

Job summary

Immatics US, Inc. in Houston, TX is seeking a Principal Business Support Specialist to provide high‑level executive and operational support to our CPO, CFO, SVP Finance and VP, HR.

This role blends the precision and discretion of an Executive Assistant with the agility of a business operations coordinator to enable leadership effectiveness and drive organizational efficiency. You will manage complex calendars, coordinate schedules, and support HR and Finance priorities across the organization.

Qualifications

• HS or equivalent is required AND 5+ years of experience supporting senior executives, preferably biotech.
• Strong calendar and travel coordination skills with discretion.
• Experience with CXO-level support is a plus.

Responsibilities

• Provide multi-faceted administrative support to ensure effective use of executive time and productive interactions with staff, partners, and external stakeholders.
• Manage complex calendars, coordinate meetings and travel across time zones.
• Prepare agendas, briefings, presentations, and follow-up actions for internal and external meetings.

Skills

Executive support

Calendar management

Travel coordination

Education

High school diploma

Bachelor's degree preferred

Tools

Outlook calendar

Concur

Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview

The Principal Business Support Specialist will provide high-level executive and operational support to our CPO, CFO, SVP Finance and VP, HR. This role combines the precision and discretion of an Executive Assistant with the agility and insight of a business operations coordinator. You will be instrumental in enabling leadership effectiveness, driving organizational efficiency, and ensuring seamless execution of critical business priorities across the People and Finance functions. This is an opportunity for a proactive, resourceful professional who thrives in a fast-paced environment and takes pride in enabling leaders and teams to perform at their best.

Schedule: Monday – Friday, 8:00 am – 5:00 pm

Reports to: Chief People Officer

Location: 13203 Murphy Road Suite 100 Stafford, TX 77477

Basic Qualifications

• HS or equivalent is required AND 5+ years of experience supporting senior executives, preferably biotech

Preferred Qualifications

• Prior experience supporting CPO, CFO or other CXO is strongly preferred
• Bachelor’s degree is preferred.
• Outlook calendaring, Concur, T&E Event planning

In this role you will support:

Executive & Administrative Efforts

Provide multi-faceted administrative support to ensure effective use of executive time and productive interactions with staff, partners, and external stakeholders. Manage complex calendars and proactively coordinate schedules, meetings, and travel across multiple time zones. Prepare agendas, briefings, presentations, and follow-up actions for internal and external meetings. Handle confidential information with discretion and serve as a trusted point of contact on behalf of the HR and Finance executives. Conduct research and information gathering on behalf of the CPO, CFO, leadership team; draft summaries, slides, and reports as needed.

HR & Finance Business

Coordinate cross-functional projects, track deliverables, and manage team workflows using project management tools. Implement and improve administrative processes to support the HR and Finance department goals. Contribute to planning and execution of team events, off‑sites, workshops, and key HR/Finance meetings.

Organizational Relationship Management

Serve as an internal liaison between the HR/Finance team and key functions including Operations, R&D, G&A and Admin Operations. Build and maintain strategic working relationships across all levels of the organization to support seamless coordination and communication. Represent the HR and Finance functions professionally and with a high degree of organizational knowledge.

Qualified candidates will participate in a structured interview process, which includes:

• An initial recruiter phone screen (conducted via video)
• A recruiter‑facilitated introduction and interview with the hiring leader and key stakeholders (via video)
• A final‑stage interview, which may include an in‑person meeting at our U.S. Headquarters in Houston, TX

Travel Required: Up to 20% travel will be required.

What do we offer?

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment
• 12 company paid holidays
• 7 days of sick time
• 100% employer‑paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
• 100% employer‑paid short- and long‑Term disability coverage
• 401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2‑3 of employment, and up to 5% of your salary from the fourth year onward of continued employment
• Partially paid parental leave for eligible employees
• Additional voluntary employee‑paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at [e-mail].

Work Authorization

Applicants must be authorized to work in the United States without the need for current or future sponsorship.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check, reference checks and pre‑employment drug screening, where permitted by applicable law. For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job‑related and consistent with business necessity.

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting‑edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.