Principal Biophysics Scientist – High-Throughput Bioassays

Scorpion Therapeutics; South Dakota; On-site; USD 109,000 - 222,000; Full time

Benefits offered by this job

Health benefits

Life/disability insurance

401(k) with company match

Time off package

Job summary

Scorpion Therapeutics located in La Jolla, CA is seeking a Principal Scientist I/II to design and optimize biophysical assays for small molecules. The role involves leading experiments, collaborating across teams, and presenting data to stakeholders.

The candidate will drive automation initiatives, manage multiple projects, and contribute to high-impact publications. Requires a PhD with 2+ years in industry and strong troubleshooting skills.

Qualifications

• Ph.D. in Biophysics, Biochemistry, or Bioengineering with 2+ years in drug discovery.
• Deep expertise in designing, validating, executing, and troubleshooting biophysical assays.
• Ability to manage multiple projects independently and adapt to evolving priorities.
• Ability to innovate; recommend and bring in new technologies.
• Strong analytical, troubleshooting, and problem-solving skills.
• Excellent communication and teamwork abilities.

Responsibilities

• Design, develop, and optimize biophysical assays (SPR, BLI) for small molecules.
• Execute routine assays to define structure-activity relationships.
• Implement and manage automation to enhance throughput and data quality.
• Collaborate with cross-functional teams to integrate new technologies and workflows.
• Analyze, interpret, and present scientific data to stakeholders.
• Maintain detailed laboratory records; contribute to reports and publications.

Job description

Scorpion Therapeutics located in La Jolla, CA is seeking a Principal Scientist I/II to design and optimize biophysical assays for small molecules. The role involves leading experiments, collaborating across teams, and presenting data to stakeholders.

The candidate will drive automation initiatives, manage multiple projects, and contribute to high-impact publications. Requires a PhD with 2+ years in industry and strong troubleshooting skills.