Director, Translational Bioanalysis & Biomarker Strategy

Scorpion Therapeutics; Bridgewater (MA); On-site; USD 250,000 - 420,000; Full time

Benefits offered by this job

Medical, dental, vision

Mental health support

Wellbeing reimbursement

401(k) with match

Annual equity awards; ESPP

Company-paid life/disability

Learning/mentorship programs

Job summary

Scorpion Therapeutics seeks a Director of Translational Bioanalytical Sciences to lead development, validation, and strategic application of bioanalytical assays across small molecules, biologics, and evolving modalities.

You will partner with cross-functional teams to shape translational strategies, oversee CROs, support regulatory interactions, and mentor teams while driving adoption of new technologies in a fast-paced clinical development program.

Qualifications

• PhD in Analytical Chemistry, PK, Pharmacology, Pharmaceutics, Bioanalytical Sciences, or related field.
• 10+ years in translational sciences, bioanalysis, biomarkers, and clinical development.
• Experience building/mentoring scientific teams.
• Expertise in LC-MS/MS across modalities.
• Regulated and non-regulated bioanalytical study design/management.
• Strong lifecycle management knowledge and regulatory guidance.
• Experience managing CRO/partner governance and outsourcing.
• Broad understanding of drug development and translation to strategy.
• Track record on global cross-functional project teams.
• Regulatory knowledge including health authority interactions (IND/CTA/NDA/BLA).

Responsibilities

• Provide scientific leadership for development/validation of bioanalytical and biomarker assays.
• Partner with cross-functional teams on Translational Bioanalytical strategies.
• Represent TBAS on global project teams for strategy and regulatory interactions.
• Lead assay development and validation with CROs/partners ensuring compliance.
• Plan and oversee regulated/non-regulated bioanalytical testing for studies.
• Support clinical study design with input into protocols and biomarker plans.
• Author/review submissions (INDs, CTAs, NDAs, etc.).
• Interpret data to inform dose selection and patient stratification.
• Establish vendor governance and oversee CROs for quality and timelines.
• Mentor and drive adoption of emerging technologies.

Skills

Scientific leadership

Cross-functional collaboration

Regulatory knowledge

Team mentoring

CRO governance

Education

PhD in Analytical Chemistry or related field

Tools

LC-MS/MS

Bioanalytical methods

Pharmacokinetics

Job description

Scorpion Therapeutics seeks a Director of Translational Bioanalytical Sciences to lead development, validation, and strategic application of bioanalytical assays across small molecules, biologics, and evolving modalities.

You will partner with cross-functional teams to shape translational strategies, oversee CROs, support regulatory interactions, and mentor teams while driving adoption of new technologies in a fast-paced clinical development program.