Postdoctoral Scientist: Ophthalmology & Gene Therapy

University of Pennsylvania Perelman School of Medicine; Pennsylvania; On-site; USD 52,000 - 66,000; Full time

Job summary

University of Pennsylvania - Perelman School of Medicine is seeking a highly motivated, full-time postdoctoral scientist to join a dynamic ophthalmology research lab led by Dr. Lucie Guo. The role focuses on molecular biology, epigenetics, gene therapy, and translational ophthalmic science.

You will receive mentorship in experimental design, grant writing, and scientific communication, while developing independent research projects and preparing for an academic career.

Qualifications

• PhD in biology, biochemistry, biophysics, pharmacology, molecular biology, genetics, neuroscience, vision science, biomedical engineering, or related field required.
• Strong experimental design and data analysis skills are essential.
• Excellent written and oral communication abilities; track record of scientific publication preferred.

Responsibilities

• Conduct independent laboratory research using molecular cloning, cell culture, CRISPR-based genome engineering, and biochemical assays.
• Perform mouse model studies, tissue collection, ocular imaging, and histologic analyses.
• Design rigorous experiments and optimize protocols; troubleshoot independently.
• Maintain accurate lab records and ensure data quality and reproducibility.
• Present progress at lab meetings and seminars; prepare figures and manuscripts for publication.

Skills

Molecular biology

CRISPR

Gene therapy

Data analysis

Scientific communication

Education

PhD in Biology or related field

Tools

PCR

Western blotting

Immunofluorescence

Cell culture

Animal handling

Job description

University of Pennsylvania - Perelman School of Medicine is seeking a highly motivated, full-time postdoctoral scientist to join a dynamic ophthalmology research lab led by Dr. Lucie Guo. The role focuses on molecular biology, epigenetics, gene therapy, and translational ophthalmic science.

You will receive mentorship in experimental design, grant writing, and scientific communication, while developing independent research projects and preparing for an academic career.