Ophthalmology Research Postdoc: Gene Therapy Focus

Upenn; Philadelphia (Philadelphia County); On-site; USD 60,000 - 75,000; Full time

Job summary

The Department of Ophthalmology at University of Pennsylvania invites applications for a full-time postdoctoral scientist to join a collaborative laboratory led by Dr. Lucie Guo.

The position focuses on molecular biology, epigenetics, gene therapy, and vision science, with mentorship in experimental design, grant writing, and career development. Responsibilities include independent research using cloning, CRISPR genome editing, cell culture, and animal studies with mouse models.

Qualifications

• PhD in biology, biochemistry, biophysics, pharmacology, molecular biology, genetics, neuroscience, or related field.
• Strong background in experimental design, data analysis and scientific communication.
• Publication record and independent research interest preferred.

Responsibilities

• Conduct independent laboratory research using cloning, CRISPR, cell culture and assays.
• Perform animal studies with mouse models, tissue collection and imaging.
• Design and optimize experiments; troubleshoot technical challenges.
• Maintain organized records, ensure data quality and reproducibility.
• Analyze data with appropriate statistics and present findings at meetings.
• Prepare figures, manuscripts and grant applications; mentor junior researchers.
• Collaborate with clinicians and researchers across disciplines.

Skills

Molecular biology techniques

PCR

CRISPR genome editing

Cell culture

Transfection

Animal research

Mouse models

Immunofluorescence

Flow cytometry

Data analysis

Education

PhD in biology/biochemistry/biophysics/neuroscience

Job description

The Department of Ophthalmology at University of Pennsylvania invites applications for a full-time postdoctoral scientist to join a collaborative laboratory led by Dr. Lucie Guo.

The position focuses on molecular biology, epigenetics, gene therapy, and vision science, with mentorship in experimental design, grant writing, and career development. Responsibilities include independent research using cloning, CRISPR genome editing, cell culture, and animal studies with mouse models.