Postdoctoral Scientist — Nanopore Proteomics & AI Sensing

imec USA; Cambridge (MA); On-site; USD 77,000 - 104,000; Full time

Benefits offered by this job

Employer-paid medical insurance

Opportunities to publish and present

Job summary

Imec USA in Cambridge, MA seeks a Postdoctoral Researcher for Nanopore Proteomics and AI-driven single-molecule sensing. You will develop CMOS nanopore platforms and machine-learning workflows to enable protein fingerprinting and classification in a high-impact, multidisciplinary setting.

The role emphasizes experimental and computational research, collaboration with international teams, and contribution to publications and future diagnostic technologies.

Qualifications

• PhD in a relevant science/engineering field.
• Hands-on nanopore sensing and single-molecule analysis experience.
• Experience analyzing complex datasets with Python or MATLAB.

Responsibilities

• Design and execute nanopore experiments using CMOS-compatible solid-state nanopore platforms.
• Characterize protein and polymer-protein translocation dynamics through nanopores under varying conditions.
• Develop experimental protocols for nanopore-based protein fingerprinting, trapping, and characterization.
• Generate and analyze large-scale single-molecule datasets acquired from high-bandwidth nanopore systems.
• Extract and characterize translocation signal features including dwell times, current blockades, event morphology, and voltage-dependent behavior.
• Develop, implement, and validate machine learning workflows for protein classification and signal interpretation.
• Investigate relationships between molecular structure, nanopore transport behavior, and measured electrical signals.
• Collaborate closely with polymer chemists, semiconductor specialists, device engineers, and life-science researchers.
• Contribute to multiplexed protein sensing assays and next-generation nanopore platforms.
• Apply quantitative and physical modeling approaches to interpret experimental results.
• Present research findings at international conferences and contribute to publications in leading scientific journals.
• Support proposal development and contribute to strategic research activities within imec’s life sciences and healthcare programs.

Skills

Nanopore sensing

Biosensors

Single-molecule analysis

Microfluidics

Electrophysiology

Python

MATLAB

Education

PhD in Physics, Bioengineering, Electrical Engineering, Nanotechnology, Biophysics, Biomedical Engineering, Computational Biology, Chemistry, or related field

Tools

Python

MATLAB

Job description

Imec USA in Cambridge, MA seeks a Postdoctoral Researcher for Nanopore Proteomics and AI-driven single-molecule sensing. You will develop CMOS nanopore platforms and machine-learning workflows to enable protein fingerprinting and classification in a high-impact, multidisciplinary setting.

The role emphasizes experimental and computational research, collaboration with international teams, and contribution to publications and future diagnostic technologies.