Postdoctoral Research Fellow Neurology CTN Lab

2200 The Brigham and Women's Hospital, Inc.; Boston (MA); On-site; USD 70,000 - 72,000; Full time

Job summary

The Brigham and Women's Hospital, Inc. invites applications for a Postdoctoral Research Fellow focused on multiple sclerosis and neuroimmunological disorders.

The team investigates EBV roles in MS, using human samples, disease models, and cutting-edge single-cell technologies. Ideal candidates have a strong background in immunology, molecular biology, and computation, with experience in proteomics, flow cytometry, and RT-qPCR.

Qualifications

• MD, PhD, or equivalent doctoral degree required.
• Experience in immunology and molecular biology techniques.
• Ability to work with human samples and/or animal models.

Responsibilities

• Single cell transcriptomic and multiome analysis.
• Proteomic analysis.
• Flow cytometry and analysis for projects.
• Cell culture and analysis for projects.
• RT-PCR and ELISA skills.
• Biostatistical analysis with biostatistics team.
• Drafting manuscripts and presenting results.

Skills

Immunology

Molecular biology

Computational biology

Single-cell analysis

Flow cytometry

RT-qPCR

Proteomics

Biostatistics

Education

MD/PhD or equivalent

Tools

Flow cytometry

RT-qPCR

Proteomics

Western blot

ELISA

Job description

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary Postdoctoral Research Fellow Position in Multiple Sclerosis and Neuroimmunological Disorders The Chitnis Translational Neuroimmunology Laboratory is seeking a highly motivated post-doctoral fellow to join the team of researchers working on multiple sclerosis and neuroimmunological disorders, with a focus on understanding the role of Epstein Barr virus in multiple sclerosis, as well as novel therapeutic targets. Studies include human control and disease samples, with correlation to clinical outcomes.

The ideal candidate will have a background in immunology basic research and/or molecular biology and computation with experience in techniques including proteomic and single cell transcriptomic analysis, flow cytometry, cell culture and RT-qPCR. The postdoctoral fellow will function as part of a team of researchers which includes bench scientists, clinicians, bioinformatics, data analysts and trainees. Prioritized candidates should demonstrate excellent scientific productivity, evidenced by high-quality publications, and be highly-motivated to conduct independent research. Candidates should have a strong background in molecular biology techniques and the ability to conduct research using human samples and/or animal models. He/she should also be competent in FACS and single-cell techniques.

Additionally, candidates should display good communication, presentation and inter-personal skills. M.D., Ph.D., or equivalent is required. A minimum two-year commitment is required.

Principal duties of responsibility include:

• Single cell transcriptomic and multiome analysis
• Proteomic analysis
• Conduct of flow cytometry and analysis for specific projects, subject groups
• Conduct of cell culture and analysis for specific projects, subject groups
• RT-PCR, Western blot, ELISA skills
• Conduct of biostatistical analysis in conjunction with biostats team
• Understanding of disease state and data variables
• Drafting manuscripts
• Scientific presentations to lab team and at conferences
• Participation in team laboratory projects as needed

Qualifications Applicants are expected to have M.D., Ph.D. or equivalent doctoral degree Prioritized candidates should demonstrate excellent scientific productivity, evidenced by high-quality publications, and be highly-motivated to conduct independent research. Candidates should have a strong background in immunology and molecular biology techniques and the ability to conduct research using animal models of disease as well as human samples. Additionally, candidates should display good communication and inter-personal skills. M.D., Ph.D., or equivalent is required. A minimum two-year commitment is required.

The salary for this position ranges from $70,000 to $71,750.

Remote Type Onsite Work Location 60 Fenwood Road

EEO Statement: 2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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