Research Fellow - Cancer Biology

5110 Massachusetts Eye and Ear Infirmary; Boston (MA); On-site; USD 72,000 - 74,000; Full time

Job summary

5110 Massachusetts Eye and Ear Infirmary seeks a research fellow to conduct independent and collaborative studies under the Principal Investigator. You will work with a team of researchers to advance knowledge and develop innovative solutions, including preparation of grant proposals and progress reports.

The role requires a PhD in molecular biology or related field, hands-on experience with animal models, and a strong background in cell culture and biochemical techniques.

Qualifications

• Doctorate in a related field is required.
• Experience with designing and executing independent and collaborative research.
• Strong analytical skills and proficiency in stats software.
• Excellent written and verbal communication abilities.
• Ability to mentor students and work in a team environment.

Responsibilities

• Design, plan, and execute research experiments aligned with departmental goals.
• Gather, analyze, and interpret data using appropriate statistical methods.
• Conduct literature reviews to inform methodologies and directions.
• Prepare and publish findings in peer‑reviewed journals; present at conferences.
• Mentor graduate and undergraduate students and assist in grant proposals.

Skills

Research techniques

Statistical analysis

Literature reviews

Written communication

Team collaboration

Education

PhD in molecular biology or related field

Tools

Statistical software

Animal models

Cell culture

Job description

Site: Massachusetts Eye and Ear Infirmary Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

Will conduct independent and collaborative research, contributing to the advancement of knowledge and the development of innovative solutions. The fellow will work under the supervision of the Principal Investigator and collaborate with a team of researchers. Does this position require Patient Care? No

Essential Functions

• Design, plan, and execute research experiments or projects in alignment with departmental goals.
• Gather, analyze, and interpret data using appropriate statistical methods and tools.
• Conduct comprehensive literature reviews to inform research direction and methodologies.
• Prepare and publish research findings in peer-reviewed journals and present at conferences and seminars.
• Work collaboratively with faculty, students, and other researchers, contributing to a positive research environment.
• Mentor graduate and undergraduate students, providing guidance on research methodologies and techniques.
• Assist in the preparation of grant proposals and funding applications to support ongoing research.
• Prepare periodic reports and documents summarizing research progress and outcomes.

Qualifications

Qualifications Education Doctorate Related Field of Study required Can this role accept experience in lieu of a degree? No Licenses and Credentials Experience Previous Research experience 3-5 years required

Knowledge, Skills and Abilities

• Demonstrated experience in research techniques, methods, or research areas relevant to the project.
• Proficient analytical skills, proficiency in statistical software, and excellent written and verbal communication skills.
• Ability to work independently as well as collaboratively within a team.
• Good interpersonal and communication skills.

Salary: $71,750.00 - $73,544.00/Annual

Additional Job Details (if applicable) Qualifications:

PhD in molecular biology, Biochemistry, biophysics, immunology, or related field strongly preferred. The ideal candidate will have demonstrated hands‑on experience with animal models and/or a strong background in cell culture and molecular biology techniques, including tissue handling, mammalian cell culture, and standard biochemical assays. Preferred qualifications include prior experience with xenograft and orthotopic murine tumor models, cancer biology research, as well as familiarity with molecular biology techniques such as Western blotting, nucleic acid extraction, single-cell RNA sequencing, spatial biology, flow cytometry, immunofluorescence, and immunohistochemistry. Exposure to biomedical imaging, quantitative assays, or interdisciplinary research environments integrating biology and technology is desirable. Strong proficiency in following experimental protocols with precision, maintaining accurate records, and working with biological samples is essential.

In vivo mouse tumor models Establishing, maintaining, and monitoring orthotopic and xenograft murine tumor models Subcutaneous, IP, and IV injections Handling and processing of mouse tissues following in vivo experiments Supporting ex vivo tissue preparation and analysis, including sample preservation for downstream assays Cell biology and in vitro systems Maintaining routine 2D and 3D mammalian cell culture Establishing and expanding primary cell lines from tumor or tissue specimens Performing cell-based assays to evaluate biological responses to therapeutic or imaging agents Supporting experimental design and execution of mechanistic studies in vitro Molecular and biochemical techniques Tissue processing for downstream molecular analyses Extraction of DNA, RNA, and proteins from tissue and cell samples Western blotting, immunodetection, and related protein analysis techniques Flow cytometry and sample preparation for immune and tumor cell profiling Supporting downstream data interpretation in collaboration with investigators

Remote Type Onsite Work Location 20 Staniford Street Scheduled Weekly Hours 40 Employee Type Regular Work Shift Day (United States of America)

EEO Statement:

5110 Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline. Combat disease. Hold a hand. Help people. Impact the world. Mass General Brigham is a passionate, welcoming community where minds meet caring hearts. Come be a part of the world’s most powerful force in medicine, where every role is important in changing lives. Our history includes New England hospitals founded over 200 years ago, some of the first and most prestigious hospitals in the world. Built on the legacy of two leading academic medical centers, we’re more than a system—we’re leaders in the practice of medicine. Mass General Brigham is committed to serving the community. We are dedicated to enhancing patient care, teaching and research, and taking a leadership role as an integrated health care system. We recognize that increasing value and continuously improving quality are essential to maintaining excellence.