Postdoctoral Research Associate — Proteomics

Ugajobsearch; Athens (GA); Hybrid; USD 54,000 - 74,000; Full time

Job summary

University of Georgia is seeking a Post Doctoral Research Associate to join the Lance Wells Lab at the CCRC to study O-GlcNAc signaling in human health and disease. The role involves advanced mass spectrometry and chemoenzymatic tagging to quantify dynamic modifications in brain tissue, with NIH and MJFF-supported projects.

The successful candidate will develop novel detection methods, generate and characterize cellular models, and contribute to publications and grant proposals while working in

Qualifications

• Ph.D. in Biochemistry, Chemistry, or related field.
• Experience in MS-based proteomics.
• Proficiency in protein purification and chemical biology labeling.

Responsibilities

• Map O-GlcNAc sites and dynamics in neuronal models of Parkinson’s and OGT - XLID.
• Develop and implement advanced chemoenzymatic tagging and protein enrichment strategies.
• Conduct high-resolution mass spectrometry (LC-MS/MS) and data analysis to identify disease-specific glycoproteomic signatures.
• Generate and characterize variant cell lines and enzymes.
• Investigate impact of specific changes in O-GlcNAc on key substrates.
• Present and publish findings.
• Grant writing.

Skills

Mass spectrometry

Education

Ph.D. in Biochemistry or related field

Tools

Protein purification

Chemoenzymatic labeling

Job description

University of Georgia is seeking a Post Doctoral Research Associate to join the Lance Wells Lab at the CCRC to study O-GlcNAc signaling in human health and disease. The role involves advanced mass spectrometry and chemoenzymatic tagging to quantify dynamic modifications in brain tissue, with NIH and MJFF-supported projects.

The successful candidate will develop novel detection methods, generate and characterize cellular models, and contribute to publications and grant proposals while working in