Postdoctoral Research Associate

Texas A&M University; Bryan (TX); On-site; USD 42,000 - 51,000; Full time

Job summary

Texas A&M University invites applications for a Postdoctoral Research Associate in the Neuroscience & Experimental Therapeutics area. The successful candidate will investigate basal ganglia and corticostriatal circuits in substance use disorders using rodent models, with state-of-the-art methods including optogenetics, chemogenetics, and slice electrophysiology.

The role involves designing experiments, training animals, and contributing to publications and presentations.

Qualifications

• PhD in neuroscience or related field is required.
• Strong verbal and written communication skills.
• Experience with rodent behavior assays and electrophysiology is preferred.

Responsibilities

• Design research experiments to study basal ganglia and corticostriatal circuits.
• Train animals for self-administration studies.
• Perform slice electrophysiology and fiber photometry experiments.

Skills

Verbal communication

Written communication

Experimental design

Education

PhD in neuroscience or related field

Tools

Imaris

Job description

Job TitlePostdoctoral Research AssociateAgencyTexas A&M University Health Science CenterDepartmentNeuroscience & Experimental TherapeuticsProposed Minimum Salary$4,166.67 monthlyJob LocationBryan, TexasJob TypeStaffJob DescriptionOur CommitmentTexas A&M University is committed to enriching the learning and working environment by promoting a culture that respects all perspectives, talents & lived experiences. Embracing varying opinions and perspectives strengthens our core values which are: Respect, Excellence, Leadership, Loyalty, Integrity, and Selfless Service.Who we areAs one of the fastest-growing academic health centers in the nation, Texas A&M Health encompasses five colleges and numerous centers and institutes working together to improve health through transformative education, innovative research and team-based health care delivery.What we wantThe Postdoctoral Research Associate, under general supervision, is responsible for conducting research into their field of expertise. This position will study the roles of the basal ganglia and corticostriatal circuit mechanisms underlying substance use disorders and neurodegenerative disease using rodent models. Research in the lab utilizes state-of-the-art technologies, including oral and intravenous alcohol and drug self-administration in operant chambers, in vivo optogenetic and chemogenetic manipulation, slice electrophysiology, viral and rodent genetics, confocal imaging to investigate circuit mechanisms of addiction and neurodegenerative disorders.What you need to knowTravel: This position may require travel.Schedule: This position may require work beyond normal office hours and/or work on weekends.Please note: This position is grant funded; future employment may be contingent upon future funding.Responsibilities:ResearchUnder general supervision, is responsible for conducting research into their field of expertise.Design research experiments.Writes and may contribute to research papers, articles, and publications.Train rats and mice to self-administer alcohol, cocaine, or opioids (e.g., morphine or fentanyl) using operant chambers.Perform slice electrophysiology recordings (e.g., whole-cell patch clamp) to assess synaptic and intrinsic properties.Design and execute fiber photometry experiments to monitor population calcium dynamics during behavior.Conduct stereotaxic surgeries for viral delivery and implantation (cannula, optical fiber, or electrode).Analyze electrophysiology and photometry data using appropriate software and statistical methods.Conduct selected behavioral assays (e.g., operant self-administration or conditioned place preference) as needed to support circuit-level studies.Lab Specific DutiesConduct stereotaxic infusion of virus or other neuronal tracers.Perform intracardial perfusion and brain fixation.Perform brain sectioning using vibratome or cryostat.Mount brain section and acquire section image using confocal microscope.Analyze confocal images using Imaris and other programsPresentationsPrepares presentation materials on research topic that may be presented to small and/or large groups.Actively participates in the preparation of required technical progress reports to research sponsors.Construct graphs with analyzed data. Write manuscript and rebuttal letters.MentoringMay assist, mentor, and/or supervise student researchers and/or graduate students who are working on research related to the project.Qualifications:Required Education and Experience:Appropriate PhD in neuroscience or related field.Preferred Qualifications:1-3 years of research experience after obtaining Ph.D. degree.Prior in-depth experience with rodent behavioral assay, including operant self-administration of alcohol or drug in rats or mice.Experience with slice electrophysiology (e.g., whole-cell patch clamp recordings).Experience with fiber photometry for monitoring neural activity in vivo.Strong experience with stereotaxic virus or drug infusion, conditioned place preference, locomotor activity measurement, T-maze and Barn's Maze. Experience with chemo genetic and optogenetic manipulation of rodent behavior, immunohistochemistry and image analysis.Trackable records on first-author publications. Knowledge of cellular, synaptic, and circuit mechanisms underlying neuropsychiatric disorders including Alzheimer's disease or alcohol, cocaine, or opioid use disorders.Knowledge of behavioral science including instrumental and pavlovian conditioning, goal-directed versus habitual behaviors, and learning and memory.Ability to conduct and analyze oral or intravenous operant drug self-administration in rats or mice, canula or optical fiber implantation, conditioned place preference or aversion, locomotor activity, T-maze or Barn's maze.Ability to write manuscript and funding.Required Knowledge, Skills, and AbilitiesExcellent verbal and written skills.Attention to detailWhy Texas A&M University?We are a prestigious university with strong traditions, Core Values, and a community of caring and collaboration. Amenities associated with a major university, such as sporting and cultural events, state-of-the-art recreation facilities, the Bush Library and Museum, and much more await you. Experience all that a big city has to offer but with a reasonable cost-of-living and no long commutes.Medical, prescription drug, dental, vision, life and AD&D, flexible spending accounts , and long-term disability insurance with Texas A&M contributing to employee health and basic life premiums12-15 days of annual paid holidaysUp to eight hours of paid sick leave and at least eight hours of paid vacation each monthAutomatic enrollment in the Teacher Retirement System of TexasHealth and Wellness: Free exercise programs and release timeProfessional Development: All employees have access to free LinkedIn Learning training, webinars, and limited financial support to attend conferences, workshops, and moreEducational release time and tuition assistance for completing a degree while a Texas A&M employeeLiving Well, a program at Texas A&M that has been built by employees, for employeesInstructions to Applicants: Applications received by Texas A&M University must either have all job application data entered, or a resume attached. Failure to provide all job application data or a complete resume could result in an invalid submission and a rejected application. We encourage all applicants to upload a resume or use a LinkedIn profile to pre-populate the online application.All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution’s verification of credentials and/or other information required by the institution’s procedures, including the completion of the criminal history check.Equal Opportunity/Veterans/Disability Employer.