Postdoctoral Fellow - Stem Cell & Organoid Research

BioSpace; Frederick (MD); Sur place; USD 53 000 - 76 000; Plein temps

Résumé du poste

Leidos Biomedical Research, Inc. in Frederick, MD is seeking a highly qualified scientist to lead intrinsic stem cell and organoid research within the LASP of the NIH SOM Initiative.

The role focuses on iPSC-derived models, metabolic regulation, and integration of multi-omics data to advance regenerative medicine and disease modeling. The successful candidate will design and optimize iPSC reprogramming, organoid culture, and metabolic profiling assays, collaborate across NIH teams, publish

Qualifications

• PhD from an accredited college or university; foreign degrees evaluated for U.S. equivalency.
• No work experience required with a doctorate.
• Experience in mammalian cell culture and aseptic technique.
• Demonstrated experience designing and independently executing scientific research projects.
• Experience with molecular and cellular biology techniques.
• Evidence of scientific productivity through peer‑reviewed publications.
• Must possess basic Microsoft Office skills.
• Ability to obtain and maintain a security clearance.

Responsabilités

• Design and independently conduct innovative research investigating metabolic regulation of human stem cell fate using iPSC-derived models.
• Develop, optimize, and characterize human iPSC reprogramming, maintenance, genome editing, directed differentiation, and organoid culture systems.
• Design and implement metabolic profiling approaches, including mitochondrial functional assays, extracellular flux analysis, metabolomics, stable isotope tracing, and complementary molecular and cellular approaches.
• Integrate transcriptomic, proteomic, metabolomic, imaging, and functional datasets to identify pathways governing stem cell fate and tissue maturation.
• Collaborate with multidisciplinary investigators across the NIH SOM Initiative to develop reproducible, scalable, and physiologically relevant stem cell and organoid platforms.
• Publish research findings in peer‑reviewed journals and present results at national and international scientific meetings.
• Contribute to grant applications, technical reports, manuscripts, and collaborative research initiatives.
• Contribute to the development and implementation of new experimental approaches and technologies.

Connaissances

Mammalian cell culture

Aseptic technique

Research design

Molecular biology

Cell biology techniques

Peer‑reviewed publications

Microsoft Office

Security clearance

Formation

PhD/Doctorate

Outils

CRISPR/Cas9

Seahorse XF

Metabolomics platforms

Organoid culture systems

Flow cytometry

High-content imaging

Description du poste

Leidos Biomedical Research, Inc. in Frederick, MD is seeking a highly qualified scientist to lead intrinsic stem cell and organoid research within the LASP of the NIH SOM Initiative.

The role focuses on iPSC-derived models, metabolic regulation, and integration of multi-omics data to advance regenerative medicine and disease modeling. The successful candidate will design and optimize iPSC reprogramming, organoid culture, and metabolic profiling assays, collaborate across NIH teams, publish