Postdoctoral Fellow - Lymphoma-Myeloma - Research

University of Texas MD Anderson Cancer Center; Houston (TX); On-site; USD 64,000 - 76,000; Full time

Job summary

University of Texas MD Anderson Cancer Center seeks a postdoctoral researcher to integrate and analyze single cell RNA-sequencing and spatial transcriptomics data from lymphoma patients. The role involves collaborating with clinicians to advance understanding of B-cell lymphoma biology and potential therapies.

The ideal candidate has a PhD in computational biology or a related field, strong coding skills in R/Python, and experience with high-performance computing and genomics data analysis.

Qualifications

• PhD in computational biology, bioinformatics, genomics, genome science or related field required.
• Strong computational background and proficiency in at least one programming language (R, Python, Perl, C++, Java).
• Experience with high-performance computing environments and large-scale genomics data analyses preferred.

Responsibilities

• Integrate and analyze single cell RNA-sequencing and spatial transcriptomics data from lymphoma patients.
• Collaborate with scientists and clinicians to develop novel strategies for lymphoma research.
• Present findings at scientific conferences and publish in high-impact journals.
• Ensure compliance with institutional policies and regulations.

Skills

Programming in R

Python

Biostatistics

Education

PhD in computational biology or related field

Tools

HPC cluster

Single-cell RNA-seq

ATAC-seq

ChIP-seq

Hi-C

Job description

The laboratory of Dr. Michael Green is focused on understanding the molecular etiology of B-cell lymphoma, Car-t Lymphoma and aims to use this knowledge to identify novel therapeutic strategies. Our laboratory employs high-throughput genomics to interrogate primary tumor specimens and transgenic mouse models; including whole genome/exome sequencing, RNA-seq, ChIP-seq, CUT&RUN and ATAC seq, as well as cutting-edge single cell approaches. This position will focus on the integration and analysis of single cell RNA-sequencing and spatial transcriptomics datasets from lymphoma patients, as a progression and expansion of our recent work. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations.

LEARNING OBJECTIVES

• Investigate the molecular, genomic, and immunological mechanisms underlying lymphoma/myeloma cancer initiation, progression, and therapeutic response.
• Apply advanced computational or experimental approaches to study lymphoma/myeloma cancer biology, tumor heterogeneity, and the tumor microenvironment.
• Collaborate with scientists and clinicians to develop innovative strategies for lymphoma/myeloma cancer early detection, interception, and treatment.
• Present research findings at scientific conferences and publish in high-impact journals.

ELIGIBILITY REQUIREMENTS

Individuals with a PhD degree in computational biology, bioinformatics, genomics, genome science or a related field are encouraged to apply. A strong computational background, proficiency in at least one programming language (e.g., R, Python, Perl, C++, Java) and knowledge of biostatistics are required.

Experience working in high-performance computing cluster environment, experience working with single cell RNA/ATAC, ChIP-seq, ATAC-seq, Hi C, or other large-scale genomics data analysis is highly preferred. A good understanding of cancer biology, cell signaling pathways, or drug response mechanisms is also preferred.

POSITION INFORMATION

MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition.

Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements.

This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html