Postdoctoral Fellow - Lymphoma-Myeloma - Research

UT MD Anderson; Houston (TX); Vor Ort; USD 64.000 - 76.000; Vollzeit

Benefits dieser Stelle

Medical insurance

Dental insurance

Paid time off

Retirement plan

Tuition benefits

Educational opportunities

Recognition programs

Zusammenfassung

University of Texas MD Anderson Cancer Center invites applications for a full-time postdoctoral position focused on the molecular etiology of B-cell lymphoma and related cancers. The role centers on integrating single-cell RNA-seq and spatial transcriptomics with computational analyses to uncover tumor heterogeneity and therapeutic opportunities.

You will work in high-throughput genomics, collaborate with clinicians, and contribute to publications and conference presentations.

Qualifikationen

• PhD in computational biology, bioinformatics, genomics or related field.
• Strong computational background and biostatistics knowledge.
• Experience with high-performance computing environments and large-scale genomics data.

Aufgaben

• Analyze and integrate single-cell RNA-seq and spatial transcriptomics datasets from lymphoma patients.
• Develop and apply computational methods to study tumor heterogeneity and microenvironment.
• Collaborate with scientists to translate findings into therapeutic insights.
• Present results at conferences and publish in high-impact journals.

Kenntnisse

Computational biology

Biostatistics

Programming (R/Python/Perl/C/C++)

Single-cell RNA-seq

Hi-C/ATAC-seq

Ausbildung

PhD in computational biology or related field

Tools

ChIP-seq

ATAC-seq

Hi-C

HPC cluster

Jobbeschreibung

The laboratory of Dr. Michael Green is focused on understanding the molecular etiology of B-cell lymphoma, Car-t Lymphoma and aims to use this knowledge to identify novel therapeutic strategies.

Our laboratory employs high-throughput genomics to interrogate primary tumor specimens and transgenic mouse models; including whole genome/exome sequencing, RNA-seq, ChIP-seq, CUT&RUN and ATAC seq, as well as cutting-edge single cell approaches. This position will focus on the integration and analysis of single cell RNA-sequencing and spatial transcriptomics datasets from lymphoma patients, as a progression and expansion of our recent work.

All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations.

LEARNING OBJECTIVES

• Investigate the molecular, genomic, and immunological mechanisms underlying lymphoma/myeloma cancer initiation, progression, and therapeutic response.
• Apply advanced computational or experimental approaches to study lymphoma/myeloma cancer biology, tumor heterogeneity, and the tumor microenvironment.
• Collaborate with scientists and clinicians to develop innovative strategies for lymphoma/myeloma cancer early detection, interception, and treatment.
• Present research findings at scientific conferences and publish in high-impact journals.

Eligibility Requirements

Individuals with a PhD degree in computational biology, bioinformatics, genomics, genome science or a related field are encouraged to apply. A strong computational background, proficiency in at least one programming language (e.g., R, Python, Perl, C++, Java) and knowledge of biostatistics are required.

Experience working in high-performance computing cluster environment, experience working with single cell RNA/ATAC, ChIP-seq, ATAC-seq, Hi C, or other large-scale genomics data analysis is highly preferred. A good understanding of cancer biology, cell signaling pathways, or drug response mechanisms is also preferred.

POSITION INFORMATION

MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000. depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits, including medical, dental, paid time off, retirement, tuition benefits, educational opportunities, and individual and team recognition

Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements.

This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html