Postdoctoral Fellow - AI-Enabled Immune Digital Twin & Organ Damage Mechanistic Model

Indiana University Bloomington; Bloomington (IN); On-site; USD 63,000 - 77,000; Full time

Job summary

Indiana University Bloomington is seeking a Postdoctoral Fellow to develop AI-enabled immune digital twin and organ-damage mechanistic models. You will link immune dynamics to organ injury in critical illness, map biomarkers to model states, and collaborate with national partners under Dr. James A.

Glazier. The role emphasizes fast, interpretable modeling using Python/Julia/R/MATLAB, plus publishing and contract-deliverable work.

Qualifications

• Ph.D. or equivalent terminal degree in quantitative, computational, or biomedical discipline.
• Programming proficiency in Python, Julia, R, or MATLAB; background in mechanistic modeling.
• Familiarity with inflammation, cytokine signaling, sepsis, or critical care biology.

Responsibilities

• Develop fast, interpretable model components linking immune dysfunction to organ injury; map clinical time-series to model states.
• Collaborate with national consortium partners; prepare milestone-ready contract deliverables and model packages.
• Write technical publications and present findings to the scientific community.

Education

Ph.D. or equivalent terminal degree in quantitative, computational, or biomedical discipline

Tools

Python

Julia

R

MATLAB

ODE/DS Modeling

QSP

Job description

Posting Details

Position Details

Title

Postdoctoral Fellow - AI-Enabled Immune Digital Twin & OrganDamage Mechanistic Model

Appointment Status

Non-Tenure Track

Department

IU Bloomington Intelligent Systems Engineering

Location

Bloomington

Position Summary

AI-Enabled Immune Digital Twin & Organ damage Mechanistic Model Scientist: Postdoctoral Fellow; Biocomplexity Institute at IndianaUniversity Bloomington (PI: Dr. James A. Glazier)

Your primary duties will be to develop biologically meaningful, interpretable model components linking immune-state dynamics to organ-damage risk (lung, kidney, liver) in critical illness under the direction of Dr. James A. Glazier. You will map clinical biomarkers to model states, define biological scoring criteria for digital twin ensembles, collaborate with national consortium partners, write technical publications, and prepare milestone-ready contract deliverables.

60% Dynamic Immune & Organ Modeling

Develop fast, interpretable ODE /network/mechanistic model modules linking immune dysfunction to organ injury; map clinical time-series and biomarkers to model states; formulate biological plausibility and scoring criteria.

40% Consortium Deliverables & Research

Prepare test cases, model packages, and model cards; write research papers; present findings; collaborate with national consortium partners in systems biology and clinical data science.

Basic Qualifications

• Ph.D. or equivalent terminal degree in quantitative, computational, or biomedical discipline.
• Programming proficiency in Python, Julia, R, or MATLAB; background in mechanistic modeling ( ODE /dynamical systems, QSP, or agent-based); familiarity with inflammation, cytokine signaling, sepsis, or critical care biology.

Salary and Rank

70,000/Postdoctoral Fellow

For Best Consideration Date

11/07/2026

Department Contact for Questions

Please contact Professor James Glazier at [e-mail] withquestions about the position.

Posting Number

IU-101730-2026