Postdoctoral Fellow

1200 The General Hospital Corporation; Boston (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

The General Hospital Corporation in Boston, MA invites applications for a postdoctoral fellow within the Charles lab to advance research on host–pathogen interactions, vaccine development, and immunology. The role includes leading analysis, manuscript preparation, and collaboration with international sites.

Responsibilities include supervising 2-3 staff, coordinating priorities, ensuring data integrity, managing grants, and training researchers.

Qualifications

• PhD in immunology, infection biology, or related field.
• 7+ years of experience in an academic, research, or related setting.
• Experience in flow cytometry and immunological assays (ELISA, multiplex beads).
• Strong track record of publications.

Responsibilities

• Lead scientific analysis and manuscript development for 1-2 projects at a time.
• Assist PI with coordinating priorities, deadlines, and workload across ongoing projects.
• Supervise 2-3 Research Technician/Assistants or students; provide training and oversight.
• Ensure data documentation and adherence to research integrity; manage grant activities.
• Collaborate with team members at US and international research sites; contribute to grant writing.

Skills

Leadership

Team collaboration

Scientific writing

Analytical thinking

Education

PhD in immunology, infection biology, or related field

Tools

Flow cytometry

Immunoassays (ELISA, multiplex beads)

Job description

Overview

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service. We invite applicants to join Mass General Brigham to contribute to high-performing teams and groundbreaking medical discoveries.

The Charles lab focuses on reducing the global burden of mucosal and enteric infections affecting resource-poor and marginalized populations. Research aims include understanding host-pathogen and immune responses during human infection by V. cholerae and Salmonella Typhi/Paratyphi A, identifying immunogenic antigens or molecular signatures for vaccine and diagnostic development, and developing rapid diagnostic and seroepidemiologic tools for use in resource-limited settings. The postdoctoral fellow will contribute to research investigations, program administration, supervision, staff training, and grant writing.

Responsibilities

• Research: Contribute directly to ongoing projects; lead scientific analysis, abstract submissions, and manuscript development for 1-2 projects at a time.
• Research Program Management: Assist PI with managing the Charles lab research portfolio by coordinating priorities, deadlines, and workload within a group of ongoing projects.
• Supervise research staff: Provide new employee training, day-to-day oversight and direction, and assistance with recruiting.
• Ensure research integrity: Data documentation, data management, and training to promote best practices and adherence.
• Grant activities: Manage and participate in collaborative grant-writing projects.
• Collaboration: Serve as a liaison among team members at US and international research sites.

Qualifications

• PhD in immunology, infection biology, or related field.
• 7+ years of experience in an academic, research, or related setting.
• Experience in flow cytometry.
• Experience in immunological assays (e.g., ELISA, multiplex-bead based assays).
• Strong track record of publications.

Desired Skills / Competencies

• Planning, organizing, and coordinating; ability to identify opportunities to improve efficiency and implement changes.
• Time management and prioritization across multiple requests; adaptability to changing priorities.
• Collaborative work style with the ability to work effectively in a team.
• Proactive problem-solving; ability to gather information, identify resources, and consider alternatives.
• Ability to work under pressure and meet short time constraints; strong sense of urgency for results.
• Excellent written and verbal communication skills.
• Cultural awareness in communication; ability to work with diverse teams.
• Analytical curiosity and willingness to learn; ability to code in R or Python.

This description indicates the general nature and level of work performed. Actual duties, responsibilities, and qualifications may vary based on need.

Working Conditions & Location

Duties will be carried out in a typical lab environment. Occasional evening or weekend work and occasional travel to international research sites may be required. There is also the opportunity to travel to scientific meetings to present research. Location: 55 Fruit Street, onsite.

Supervisory Responsibility

The candidate will provide daily supervision, guidance, and expertise for 2-3 Research Technician/Assistants or students.

EEO Statement

The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, or other status protected by law. Reasonable accommodations are provided to participate in the job application or interview process and to perform essential job functions, as requested. For accommodation requests, contact Human Resources at [phone].