Postdoc: Protein Biochemistry, Enzymology & Biophysics

Georgia Institute of Technology; Atlanta (GA); In loco; USD 52.000 - 70.000; Tempo pieno

Descrizione del lavoro

Georgia Tech’s School of Biological Sciences seeks a postdoctoral fellow with expertise in protein biochemistry, enzymology, assay development, and biophysical characterization to support target validation and drug discovery programs.

The successful candidate will independently design experiments, generate high-quality data, and contribute to multidisciplinary scientific efforts across chemistry, computation, and cell biology teams at Georgia Tech in Atlanta.

Competenze

• PhD in Biochemistry, Biophysics, Enzymology, Chemical Biology, or a related discipline.
• Strong hands-on experience in recombinant protein production, enzymology, assay development, and biophysical characterization.
• Excellent problem-solving, data analysis, organizational, and communication skills.
• Ability to work independently while contributing effectively within interdisciplinary teams.

Mansioni

• Clone, express, purify, and characterize recombinant proteins using bacterial, insect, and mammalian expression systems.
• Develop and execute biochemical and biophysical assays, including enzyme activity assays, TR-FRET, fluorescence polarization, SPR, ITC, DSF, NMR, mass photometry and mass spectrometry.
• Perform steady-state and pre-steady-state enzyme kinetics, inhibition mechanism studies, and quantitative analysis of molecular interactions.
• A knowledge of structure solution approaches, X-ray crystallography, SAXS and cryo-EM, is desirable.
• Analyze, interpret, and communicate experimental results through project meetings, reports, presentations, and publications.
• Maintain accurate laboratory records, experimental protocols, and data documentation.
• Contribute to laboratory operations, including reagent preparation, equipment upkeep, inventory management, and procurement.
• Collaborate effectively with chemists, computational scientists, and cell biologists across multiple research programs.

Conoscenze

Recombinant protein production

Enzymology

Assay development

Biophysical characterization

Data analysis

Communication skills

Formazione

PhD in Biochemistry, Biophysics, Enzymology, Chemical Biology, or related

Strumenti

TR-FRET

Fluorescence polarization

SPR

ITC

DSF

NMR

Mass spectrometry

Descrizione del lavoro

Georgia Tech’s School of Biological Sciences seeks a postdoctoral fellow with expertise in protein biochemistry, enzymology, assay development, and biophysical characterization to support target validation and drug discovery programs.

The successful candidate will independently design experiments, generate high-quality data, and contribute to multidisciplinary scientific efforts across chemistry, computation, and cell biology teams at Georgia Tech in Atlanta.