Postdoc: GPCR Structural Biologist & Membrane Protein Expert

Medical College of Wisconsin; Milwaukee (WI); On-site; USD 52,000 - 68,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Paid vacation and holidays

Tuition reimbursement

Parental leave

Employee assistance program

Pet insurance

Job summary

The Medical College of Wisconsin (MCW) invites applications for a postdoctoral fellowship in the Zhu Lab to investigate the molecular mechanisms of membrane protein complexes, with a focus on G protein-coupled receptors (GPCRs) and related membrane proteins.

The project combines cryo-EM, biochemical and cell biology assays, and computational modeling to understand signaling and guide therapeutic development.

Qualifications

• PhD in a scientific field is required.
• Postdoctoral experience in structural biology is preferred.
• Experience with cryo-EM and/or X-ray crystallography is advantageous.

Responsibilities

• Design, plan, and execute independent research projects on GPCRs and cell signaling.
• Perform membrane protein expression, purification, and structural studies using cryo-EM and/or crystallography.
• Apply computational modeling and integrate structural, biochemical, and cell biology data.
• Analyze and interpret experimental data; develop and optimize methodologies.
• Prepare manuscripts, reports, and presentations of research findings.
• Participate in lab meetings and collaborate with team members.
• Assist in grant writing and fellowship applications.
• Mentor and train junior lab members as appropriate.
• Maintain laboratory organization, supplies, and experimental workflows.

Skills

Structural biology

Protein expression & purification

Data analysis

Scientific writing

Critical thinking

Cryo-EM workflows

Independent research

Collaborations

Education

PhD in a scientific field

Job description

The Medical College of Wisconsin (MCW) invites applications for a postdoctoral fellowship in the Zhu Lab to investigate the molecular mechanisms of membrane protein complexes, with a focus on G protein-coupled receptors (GPCRs) and related membrane proteins.

The project combines cryo-EM, biochemical and cell biology assays, and computational modeling to understand signaling and guide therapeutic development.