Postdoc: CNS Gene Delivery & AAV Engineering

Broad Institute; Cambridge (MA); Hybrid; USD 60,000 - 80,000; Full time

Benefits offered by this job

Medical, dental, vision insurance

401(k) retirement plan

Paid holidays and time off

Parental and family care leave

Job summary

The Broad Institute’s Deverman lab is seeking a postdoctoral researcher or research scientist to join a dynamic, multi-disciplinary team focused on developing AAV vectors for targeted gene expression in CNS neuronal populations. The role covers project planning, hands-on bench work, data reporting, and manuscript contributions within Broad’s collaborative ecosystem.

Candidates will work on gene regulatory elements, custom capsids, and collaboration across Harvard/MIT labs, with opportunities for

Qualifications

• Molecular biology techniques demonstrated in published work.
• Experience with gene delivery vectors or AAV systems is desirable.
• Familiarity with high-throughput screening and NGS methods.
• Hands-on experience with in vivo models and/or brain injections.
• Strong collaboration and communication in a multidisciplinary team.

Responsibilities

• Develop and refine high-throughput methods to create AAV capsids and gene expression systems.
• Apply gene delivery strategies to in vivo and in vitro CNS models.
• Perform molecular biology workflows including PCR, RNA/DNA extraction, and sequencing.
• Oversee data collection, analysis, and reporting to leadership and collaborators.
• Contribute to manuscripts, presentations, and funding reports.
• Supervise and mentor research staff and associates.

Skills

Molecular biology techniques

NGS / high-throughput screening

Immunohistochemistry / in situ

Stereotaxic injections

Bioinformatics knowledge

Collaboration in multidisciplinary 팀

Communication skills

Education

PhD in Molecular Biology / Neuroscience

Job description

The Broad Institute’s Deverman lab is seeking a postdoctoral researcher or research scientist to join a dynamic, multi-disciplinary team focused on developing AAV vectors for targeted gene expression in CNS neuronal populations. The role covers project planning, hands-on bench work, data reporting, and manuscript contributions within Broad’s collaborative ecosystem.

Candidates will work on gene regulatory elements, custom capsids, and collaboration across Harvard/MIT labs, with opportunities for