CNS Gene Therapy Biodistribution Scientist (Postdoc)

BioSpace; Boston (MA); On-site; USD 58,000 - 123,000; Full time

Job summary

Lilly in Boston is seeking a Postdoctoral Scientist to join the DDCS organization, focusing on CNS gene therapy biodistribution and molecular bioanalysis. You will work hands-on in preclinical CNS programs and collaborate across functional teams.

The role emphasizes designing assays for AAV/LNP distribution, applying PCR/qPCR/ddPCR, ELISA, IHC, and NGS, with CRO oversight and rigorous data practices. This position offers publication opportunities and a path toward translational insight.

Qualifications

• PhD in relevant life sciences.
• Experience in AAV biodistribution analysis.
• Hands-on experience with PCR/qPCR/ddPCR, ELISA, IHC, NGS.

Responsibilities

• Design and execute CNS gene therapy biodistribution studies with DoE principles.
• Troubleshoot assay performance and data variability.
• Oversee tissue collection, sample processing, and downstream molecular analyses.
• Interface with external CROs for in-vivo studies and ensure data quality.
• Collaborate with cross-functional teams to inform translational strategies.
• Communicate findings through presentations and written summaries.

Skills

AAV biodistribution

Molecular bioanalysis

PCR/qPCR/ddPCR

ELISA & IHC

NGS

Education

PhD in Life Sciences

Tools

PCR/qPCR/ddPCR

ELISA

IHC

NGS

LC-MS

Job description

Lilly in Boston is seeking a Postdoctoral Scientist to join the DDCS organization, focusing on CNS gene therapy biodistribution and molecular bioanalysis. You will work hands-on in preclinical CNS programs and collaborate across functional teams.

The role emphasizes designing assays for AAV/LNP distribution, applying PCR/qPCR/ddPCR, ELISA, IHC, and NGS, with CRO oversight and rigorous data practices. This position offers publication opportunities and a path toward translational insight.