Post Doc in Immunology and Immunoengineering

University of North Carolina at Chapel Hill DPMP; Chapel Hill (NC); On-site; USD 60,000 - 70,000; Full time

Job summary

The Ainslie Lab at the University of North Carolina at Chapel Hill is seeking two postdoctoral researchers to join an interdisciplinary program at the intersection of immunology and drug delivery. Projects span biomaterials modulating CAR-T/NKT cells for glioblastoma therapy and tolerogenic pathways for an inverse vaccine against autoimmune diseases.

Ideal candidates have a background in flow cytometry, animal models, and related immunology techniques, with hands-on training across formulation

Qualifications

• Background in one or more of the listed techniques (flow cytometry, animal models, mammalian cell culture, ELISA, immune-cell isolation and culture, vaccines, drug delivery systems, immunological assays, in vivo evaluation).
• Experience with flow cytometry and animal studies is particularly desirable.

Responsibilities

• Contribute to formulation development and physicochemical characterization.
• Perform cell-based assays and immunological mechanistic studies.
• Conduct animal studies and translational evaluation as part of a collaborative team.

Skills

flow cytometry

animal models

cell culture

ELISA

immune-cell isolation

vaccines

drug delivery systems

immunological assays

in vivo evaluation

Job description

Postdoctoral Researcher Openings

The Ainslie Lab (https://ainslielab.web.unc.edu/) at the University of North Carolina at Chapel Hill has two postdoctoral researcher openings. We are seeking motivated scientists — including engineers, chemists, biochemists, and immunologists — to contribute to exciting interdisciplinary projects at the intersection of immunology and drug delivery.

Projects are supported by two NIH-funded grants:

• Development of biomaterials to modulate CAR-T/NKT cells for glioblastoma therapy and immune mechanistic evaluation of epitope spreading.
• Evaluation of mechanistic tolerogenic pathways invoked by biomaterials for generation of an inverse vaccine to treat multiple sclerosis and other autoimmune diseases.

We investigate these applications both in vitro and in vivo.

Candidates with a background in one or more of the following techniques are encouraged to apply: flow cytometry, animal models, mammalian cell culture, ELISA, immune-cell isolation and culture, vaccines, drug delivery systems, immunological assays, and in vivo evaluation of therapeutic or vaccine candidates. Experience with flow cytometry and animal studies is particularly desirable.

Postdoctoral researchers will join a collaborative, interdisciplinary team and receive hands-on training across the full research process, including formulation development, physicochemical characterization, cell-based assays, immunological mechanistic studies, animal studies, and translational evaluation.

The Ainslie Lab is based in the heart of the medical campus at the University of North Carolina at Chapel Hill, located in the Research Triangle (Chapel Hill – Raleigh – Durham). The Research Triangle is home to more than 675 life-science companies, 24,000 industry employees, and nearly $10 billion in regional economic output, offering exceptional access to leading academic, biotechnology, pharmaceutical, and translational research partners.

Start date: Immediate to flexible